⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2762032 | 1.00 | — | — | |
| SCHEMBL6013726 | 1.00 | — | — | |
| SCHEMBL1040949 | 0.78 | — | — | |
| SCHEMBL3734197 | 0.78 | — | — | |
| SCHEMBL19514784 | 0.74 | — | — | |
| SCHEMBL270893 | 0.73 | — | — | |
| SCHEMBL6037216 | 0.72 | TDP1 (0.35) | — | |
| SCHEMBL181898 | 0.69 | — | — | |
| SCHEMBL2427812 | 0.69 | — | — | |
| SCHEMBL61261 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012085191-A1 | CRYSTALLINE FORM OF PRAVASTATINE AND PROCESS FOR THE PREPARATION THEREOF | DSM SINOCHEM PHARMACEUTICALS NETHERLANDS B.V. (NL) | 2012-06-28 | — | — | WO | disclosed |
| EP-2274267-A1 | PRAVASTATIN EXTRACTION | DSM IP Assets B.V. (NL) | 2011-01-19 | — | — | EP | disclosed |
| WO-2009121870-A1 | PRAVASTATIN EXTRACTION | DSM IP ASSETS B.V. (NL) | 2009-10-08 | — | — | WO | disclosed |
| WO-2009068556-A1 | PURIFICATION OF PRAVASTATIN | DSM IP ASSETS B.V. (NL) | 2009-06-04 | — | — | WO | disclosed |