⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7540941 | 0.87 | — | — | |
| SCHEMBL270893 | 0.86 | — | — | |
| SCHEMBL181898 | 0.81 | — | — | |
| SCHEMBL3475221 | 0.81 | — | — | |
| SCHEMBL61261 | 0.81 | — | — | |
| SCHEMBL19514784 | 0.81 | — | — | |
| SCHEMBL2762032 | 0.78 | — | — | |
| SCHEMBL1029264 | 0.78 | — | — | |
| SCHEMBL6013726 | 0.78 | — | — | |
| SCHEMBL667574 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117986153-A | Ionizable cationic lipid compound, and preparation method and application thereof | 晟迪生物医药(苏州)有限公司 | 2024-05-07 | — | — | CN | disclosed |
| CN-111032671-B | Protected tetraose, method for the production thereof and use thereof as a substrate for transglucosidase receptors in the chemoenzymatic synthesis of shigella flexneri-specific oligosaccharides | 巴斯德研究所 | 2024-01-12 | — | — | CN | disclosed |
| US-20240002423-A1 | PROTECTED TETRASACCHARIDES, THEIR PROCESS OF PREPARATION AND THEIR USE AS TRANSGLUCOSYLASE ACCEPTOR SUBSTRATES IN THE CHEMO-ENZYMATIC SYNTHESIS OF SHIGELLA FLEXNERI SPECIFIC OLIGOSACCHARIDES | PASTEUR INSTITUT (FR) | 2024-01-04 | — | — | US | disclosed |
| US-11834468-B2 | Protected tetrasaccharides, their process of preparation and their use as transglucosylase acceptor substrates in the chemo-enzymatic synthesis of Shigella flexneri specific oligosaccharides | INSTITUT PASTEUR (FR) | 2023-12-05 | — | — | US | disclosed |
| CN-107849594-B | Deamination of organophosphorus nucleosides | 科技学专业学院有限公司 | 2022-01-18 | — | — | CN | disclosed |
| US-20200165285-A1 | PROTECTED TETRASACCHARIDES, THEIR PROCESS OF PREPARATION AND THEIR USE AS TRANSGLUCOSYLASE ACCEPTOR SUBSTRATES IN THE CHEMO-ENZYMATIC SYNTHESIS OF SHIGELLA FLEXNERI SPECIFIC OLIGOSACCHARIDES | INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT (FR) | 2020-05-28 | — | — | US | disclosed |
| EP-3649141-A1 | PROTECTED TETRASACCHARIDES, THEIR PROCESS OF PREPARATION AND THEIR USE AS TRANSGLUCOSYLASE ACCEPTOR SUBSTRATES IN THE CHEMO-ENZYMATIC SYNTHESIS OF SHIGELLA FLEXNERI SPECIFIC OLIGOSACCHARIDES | Institut Pasteur (FR) | 2020-05-13 | — | — | EP | disclosed |
| CN-111032671-A | Protected tetrasaccharide, method for its preparation, and use thereof as a substrate for the transglucosylase receptor in the chemoenzymatic synthesis of shigella flexneri-specific oligosaccharides | 巴斯德研究所 | 2020-04-17 | — | — | CN | disclosed |
| WO-2019007999-A1 | PROTECTED TETRASACCHARIDES, THEIR PROCESS OF PREPARATION AND THEIR USE AS TRANSGLUCOSYLASE ACCEPTOR SUBSTRATES IN THE CHEMO-ENZYMATIC SYNTHESIS OF SHIGELLA FLEXNERI SPECIFIC OLIGOSACCHARIDES | INSTITUT PASTEUR (FR) | 2019-01-10 | — | — | WO | disclosed |
| US-20120142911-A1 | SYNTHESIS OF TTX INTERMEDIATES | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (ES) | 2012-06-07 | — | — | US | disclosed |
| WO-2007054517-A1 | SYNTESIS OF TETRODOTOXIN , ITS ANALOGUES AND INTERMEDIATES THEREOF | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2007-05-18 | — | — | WO | disclosed |
| EP-1785427-A1 | Syntesis of tetrodotoxin, its analogues and intermediates thereof | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2007-05-16 | — | — | EP | disclosed |
| EP-1747197-A1 | REGIOSELECTIVE FUNCTIONALISATION AND PROTECTION OF SPIROLACTAMS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2007-01-31 | — | — | EP | disclosed |
| US-20060148778-A1 | Ultraviolet radiation absorbers; such as 1 azaspiro(3,5)nona-5,8-dione derivative substituted in first position with oxy, thio or carbonyl group | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2006-07-06 | — | — | US | disclosed |
| EP-1676836-A1 | Regioselective hydroxylation, functionalisation and protection of spirolactams II | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2006-07-05 | — | — | EP | disclosed |
| WO-2006065357-A1 | METHOD OF MAKING NANOCOMPOSITES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2006-06-22 | — | — | WO | disclosed |
| US-20060128867-A1 | Method of making composites and nanocomposites | 3M INNOVATIVE PROPERTIES COMPANY | 2006-06-15 | — | — | US | disclosed |
| US-20050261492-A1 | Regioselective hydroxylation, functionalisation and protection of spirolactams | LABORATORIES DEL DR. ESTEVE, S.A. (ES) | 2005-11-24 | — | — | US | disclosed |
| EP-1598336-A1 | Regioselective hydroxylation, functionalisation and protection of spirolactams | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2005-11-23 | — | — | EP | disclosed |
| WO-2005108357-A1 | REGIOSELECTIVE FUNCTIONALISATION AND PROTECTION OF SPIROLACTAMS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2005-11-17 | — | — | WO | disclosed |