Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.40 |
| ▸ | HTT | P42858 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10293229 | 0.84 | KMT2A (0.39) | ALDH1A1MAPTTSHRMAPK1HSD17B10 | |
| SCHEMBL11990825 | 0.81 | KMT2A (0.41) | ALDH1A1MAPTTSHRMAPK1HSD17B10 | |
| SCHEMBL10292538 | 0.80 | KMT2A (0.40) | ALDH1A1MAPTTSHRMAPK1HSD17B10 | |
| SCHEMBL11990832 | 0.76 | KMT2A (0.39) | ALDH1A1MAPTTSHRMAPK1HSD17B10 | |
| SCHEMBL10292521 | 0.75 | KMT2A (0.42) | ALDH1A1MAPTTSHRMAPK1HSD17B10 | |
| SCHEMBL10292545 | 0.75 | KMT2A (0.43) | ALDH1A1HTTMAPTTSHRMAPK1 | |
| SCHEMBL11990856 | 0.75 | KMT2A (0.43) | ALDH1A1HTTMAPTTSHRMAPK1 | |
| SCHEMBL10292841 | 0.74 | KMT2A (0.38) | ALDH1A1MAPTTSHRMAPK1HSD17B10 | |
| SCHEMBL10003686 | 0.74 | PTGES (0.48) | ALDH1A1HTTMAPTTSHRHSD17B10 | |
| SCHEMBL10292544 | 0.74 | KMT2A (0.42) | ALDH1A1HTTMAPTTSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2471793-A1 | FUSED HETEROCYCLIC RING DERIVATIVE AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2012-07-04 | — | — | EP | disclosed |