Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.60 |
| ▸ | HPGD | P15428 | 9/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.58 |
| ▸ | MEN1 | O00255 | 6/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10195012 | 0.89 | ALDH1A1 (0.72) | ALDH1A1HPGDSMN1; SMN2USP2KMT2A | |
| SCHEMBL1753628 | 0.87 | HPGD (0.76) | ALDH1A1HPGDSMN1; SMN2USP2KMT2A | |
| SCHEMBL10192065 | 0.87 | ALDH1A1 (0.71) | ALDH1A1HPGDSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL257545 | 0.85 | HPGD (0.80) | ALDH1A1HPGDSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL20460439 | 0.85 | HPGD (0.80) | ALDH1A1HPGDSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL13536268 | 0.85 | HPGD (0.80) | ALDH1A1HPGDSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL12354846 | 0.85 | HPGD (0.80) | ALDH1A1HPGDSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL1447377 | 0.82 | ALDH1A1 (0.55) | ALDH1A1HPGDSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL22518388 | 0.81 | MEN1 (0.59) | ALDH1A1SMN1; SMN2USP2KMT2AMEN1 | |
| Bromide SCHEMBL22664303 | 0.79 | MEN1 (0.58) | ALDH1A1SMN1; SMN2USP2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2471787-A1 | New compounds | Boehringer Ingelheim International GmbH (DE) | 2012-07-04 | — | — | EP | disclosed |