Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5953329 | 0.87 | ALDH1A1 (0.72) | ALDH1A1HSD17B10TDP1TSHRCYP3A4 | |
| SCHEMBL27866639 | 0.83 | ALDH1A1 (0.54) | ALDH1A1HSD17B10TDP1TSHRCYP3A4 | |
| Hydrochloric Acid SCHEMBL11395642 | 0.81 | ALDH1A1 (0.52) | ALDH1A1HSD17B10TDP1TSHRCYP3A4 | |
| SCHEMBL39430 | 0.80 | TDP1 (0.72) | ALDH1A1HSD17B10TDP1TSHRCYP3A4 | |
| SCHEMBL1028447 | 0.78 | ALDH1A1 (0.56) | ALDH1A1HSD17B10TDP1TSHRCYP3A4 | |
| SCHEMBL9877223 | 0.78 | ALDH1A1 (0.44) | ALDH1A1HSD17B10TDP1TSHRCYP3A4 | |
| SCHEMBL9877687 | 0.78 | ALDH1A1 (0.50) | ALDH1A1HSD17B10TDP1TSHRCYP3A4 | |
| SCHEMBL638296 | 0.77 | ALDH1A1 (0.44) | ALDH1A1HSD17B10TDP1TSHRCYP3A4 | |
| SCHEMBL18893124 | 0.75 | TDP1 (0.48) | ALDH1A1HSD17B10TDP1TSHRCYP3A4 | |
| SCHEMBL8585221 | 0.74 | TDP1 (0.64) | ALDH1A1HSD17B10TDP1TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1474377-B1 | NITROSOPHENOLS AND C-NITROSOANILINES AS POLYMERIZATION INHIBITORS | CHEMTURA CORP (US) | 2011-01-19 | — | — | EP | claimed |
| US-7125475-B2 | Nitrosophenols and C-nitrosoanilines as polymerization inhibitors | CROMPTON CORPORATION (US) | 2006-10-24 | — | — | US | claimed |
| EP-1474377-A1 | NITROSOPHENOLS AND C-NITROSOANILINES AS POLYMERIZATION INHIBITORS | Crompton Corporation (US) | 2004-11-10 | — | — | EP | claimed |
| WO-2003070687-A1 | NITROSOPHENOLS AND C-NITROSOANILINES AS POLYMERIZATION INHIBITORS | CROMPTON CORPORATION (US) | 2003-08-28 | — | — | WO | claimed |
| US-20030155227-A1 | Nitrosophenols and C-nitrosoanilines as polymerization inhibitors | CROMPTON CORPORATION | 2003-08-21 | — | — | US | claimed |
| CN-106999852-B | Process for improved reactive monomer production | 赢创德固赛有限公司 | 2019-12-06 | — | — | CN | disclosed |
| US-20180361319-A1 | METHOD FOR IMPROVED REACTVE MONOMER PRODUCTION WITH MEMBRANE FILTRATION | EVONIK DEGUSSA GMBH (DE) | 2018-12-20 | — | — | US | disclosed |
| EP-3197596-B1 | METHOD FOR IMPROVED REACTIVE MONOMER PRODUCTION WITH MEMBRANE FILTRATION | EVONIK DEGUSSA GMBH (DE) | 2018-11-07 | — | — | EP | disclosed |
| US-20170144984-A1 | MODULATORS OF THE RELAXIN RECEPTOR 1 | THE UNITED STATES OF AMERICA AS REPRESENTED BY SECRETARY DEPT OF HEALTH AND HUMAN SERVICE (US) | 2017-05-25 | — | — | US | disclosed |
| EP-2993164-B1 | Phenolic (thio) acetals as inhibitors of the polymerisation of olefinically unsaturated monomers | EVONIK DEGUSSA GMBH (DE) | 2017-02-15 | — | — | EP | disclosed |
| EP-2993164-A1 | Phenolic (thio) acetals as inhibitors of the polymerisation of olefinically unsaturated monomers | Evonik Degussa GmbH (DE) | 2016-03-09 | — | — | EP | disclosed |
| EP-1474377-B1 | NITROSOPHENOLS AND C-NITROSOANILINES AS POLYMERIZATION INHIBITORS | CHEMTURA CORP (US) | 2011-01-19 | — | — | EP | disclosed |
| CN-1013109-B | Preparation method of N-monosubstituted p-phenylenediamine compound | UNIROYAL CHEM CO INC (US) | 1991-07-10 | — | — | CN | disclosed |
| US-5001171-A | Process, modified rubbers and rubber compositions | BRIDGESTONE/FIRESTONE, INC. (US) | 1991-03-19 | — | — | US | disclosed |
| EP-0208456-B1 | PROCESS FOR MAKING N-MONOSUBSTITUTED P-PHENYLENEDIAMINES | UNIROYAL CHEMICAL COMPANY, Inc. (US) | 1990-06-06 | — | — | EP | disclosed |
| EP-0319733-A2 | Process, modified rubbers and rubber compositions | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1989-06-14 | — | — | EP | disclosed |
| US-4788229-A | BLENDING MIXTURES OF UNCURED ELASTOMERS AND FILLERS CONTAINING ELASTOMER-FILLER LINKAGE PROMOTERS; TIRES; FRICTION RESISTANCE; REDUCED HYSTERESIS | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1988-11-29 | — | — | US | disclosed |
| CN-86107268-A | The preparation method of the single substituted p-phenylenediamine compounds of N- | — | 1988-05-04 | — | — | CN | disclosed |
| US-4723040-A | REACTING P-NITROSO-N-MONO SUBSTITUTED ANILINE WITH PRIMARY OR SECONDARY ALCOHOL | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1988-02-02 | — | — | US | disclosed |
| EP-0208456-A2 | Process for making n-monosubstituted p-phenylenediamines | UNIROYAL CHEMICAL COMPANY, Inc. (US) | 1987-01-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180361319-A1 | METHOD FOR IMPROVED REACTVE MONOMER PRODUCTION WITH MEMBRANE FILTRATION | PUF60, MAX, SAMM50 | ALDH1A1 4013/4885HSD17B10 2120/4885TDP1 3775/4885 |
| US-20170144984-A1 | MODULATORS OF THE RELAXIN RECEPTOR 1 | RXFP1, RXFP2, RXFP3 | ALDH1A1 2561/4885HSD17B10 2635/4885TDP1 860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.