Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 6/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8505216 | 1.00 | TSHR (0.48) | TSHRALDH1A1CYP3A4NAAATDP1 | |
| SCHEMBL6567582 | 1.00 | TSHR (0.48) | TSHRALDH1A1CYP3A4NAAATDP1 | |
| SCHEMBL8505895 | 1.00 | TSHR (0.48) | TSHRALDH1A1CYP3A4NAAATDP1 | |
| SCHEMBL2513161 | 1.00 | TSHR (0.48) | TSHRALDH1A1CYP3A4NAAATDP1 | |
| SCHEMBL8507336 | 1.00 | TSHR (0.48) | TSHRALDH1A1CYP3A4NAAATDP1 | |
| SCHEMBL1729891 | 1.00 | TSHR (0.48) | TSHRALDH1A1CYP3A4NAAATDP1 | |
| SCHEMBL8508151 | 1.00 | TSHR (0.48) | TSHRALDH1A1CYP3A4NAAATDP1 | |
| SCHEMBL8505503 | 1.00 | TSHR (0.48) | TSHRALDH1A1CYP3A4NAAATDP1 | |
| SCHEMBL284653 | 1.00 | TSHR (0.48) | TSHRALDH1A1CYP3A4NAAATDP1 | |
| SCHEMBL8505232 | 1.00 | TSHR (0.48) | TSHRALDH1A1CYP3A4NAAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778764-B1 | COATINGS FOR IMPLANTABLE DEVICES COMPRISING POLY(HYDROXY-ALKANOATES) AND DIACID LINKAGES | ABBOTT CARDIOVASCULAR SYSTEMS (US) | 2011-01-19 | — | — | EP | claimed |
| US-6932974-B2 | Method of preventing adhesions with absorbable polyoxaesters | ETHICON, INC. (US) | 2005-08-23 | — | — | US | disclosed |
| EP-1242505-B1 | METHOD FOR THE CONTINUOUS PRODUCTION OF COPOLYAMIDES BASED ON A LACTAME (I), A DIAMINE (II) AND A DICARBOXYLIC ACID (III) | BASF AG (DE) | 2003-06-18 | — | — | EP | disclosed |
| EP-1280846-A1 | METHOD FOR PRODUCING A POLYMER, USING CAPROLACTAM | BASF AKTIENGESELLSCHAFT (DE) | 2003-02-05 | — | — | EP | disclosed |
| EP-1242505-A1 | METHOD FOR THE CONTINUOUS PRODUCTION OF COPOLYAMIDES BASED ON A LACTAME (I), A DIAMINE (II) AND A DICARBOXYLIC ACID (III) | BASF AKTIENGESELLSCHAFT (DE) | 2002-09-25 | — | — | EP | disclosed |
| US-6403655-B1 | Method of preventing adhesions with absorbable polyoxaesters | ETHICON, INC. | 2002-06-11 | — | — | US | disclosed |
| WO-2001083589-A1 | METHOD FOR PRODUCING A POLYMER, USING CAPROLACTAM | BASF AKTIENGESELLSCHAFT (DE) | 2001-11-08 | — | — | WO | disclosed |
| US-20010012511-A1 | Method of preventing adhesions with absorbable polyoxaesters | BEZWADA RAO S (US) | 2001-08-09 | — | — | US | disclosed |
| WO-2001040355-A1 | METHOD FOR THE CONTINUOUS PRODUCTION OF COPOLYAMIDES BASED ON A LACTAME (I), A DIAMINE (II) AND A DICARBOXYLIC ACID (III) | BASF AKTIENGESELLSCHAFT (DE) | 2001-06-07 | — | — | WO | disclosed |
| US-6224894-B1 | MEDICAL EQUIPMENT | ETHICON, INC. | 2001-05-01 | — | — | US | disclosed |
| US-6147168-A | Copolymers of absorbable polyoxaesters | ETHICON, INC. (US) | 2000-11-14 | — | — | US | disclosed |
| US-6100346-A | Copolymers of polyoxaamides | ETHICON, INC. (US) | 2000-08-08 | — | — | US | disclosed |
| US-6074660-A | Absorbable polyoxaesters containing amines and/ or amido groups | ETHICON, INC. (US) | 2000-06-13 | — | — | US | disclosed |
| US-5869421-A | A MATRIX RESIN AND A DISPERSION RESIN HAVING A GLASS TRANSITION TEMPERATURE HIGHER AND DISPERSED IN THE MATRIX AS RESIN AGGREGATES; EXCELLENT ERASING; HEAT RESISTANCE; STORAGE STABILITY; DURABILITY | RICOH COMPANY, LTD. (JP) | 1999-02-09 | — | — | US | disclosed |
| EP-0082983-B1 | CURABLE SYNTHETIC RESIN COMPOSITIONS AND AGENTS FOR CURABLE SYNTHETIC RESIN COMPOSITIONS BASED ON PREPOLYMERIC POLYETHER-URETHANE-UREA AMINES AND EPOXIDE RESINS AN/OR AROMATIC CARBAMIC-ACID ARYL ESTERS | SCHERING AKTIENGESELLSCHAFT (DE) | 1987-02-04 | — | — | EP | disclosed |
| EP-0084106-B1 | CURABLE MIXTURES OF SYNTHETIC RESINS AND MEANS FOR CURABLE MIXTURES OF SYNTHETIC RESINS ON THE BASIS OF POLYETHERURETHANEUREA-AMINE PREPOLYMERS AND EPOXY RESINS | SCHERING AKTIENGESELLSCHAFT (DE) | 1986-09-10 | — | — | EP | disclosed |
| EP-0045383-B1 | HOT MELT ADHESIVE FOR JOINING TEXTILES | SCHERING AKTIENGESELLSCHAFT (DE) | 1983-09-14 | — | — | EP | disclosed |
| EP-0084106-A1 | Curable mixtures of synthetic resins and means for curable mixtures of synthetic resins on the basis of polyetherurethaneurea-amine prepolymers and epoxy resins | SCHERING AKTIENGESELLSCHAFT (DE) | 1983-07-27 | — | — | EP | disclosed |
| EP-0082983-A1 | Curable synthetic resin compositions and agents for curable synthetic resin compositions based on prepolymeric polyether-urethane-urea amines and epoxide resins an/or aromatic carbamic-acid aryl esters | SCHERING AKTIENGESELLSCHAFT (DE) | 1983-07-06 | — | — | EP | disclosed |
| EP-0045383-A2 | Hot melt adhesive for joining textiles | SCHERING AKTIENGESELLSCHAFT (DE) | 1982-02-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010012511-A1 | Method of preventing adhesions with absorbable polyoxaesters | EPCAM, CDH1, DSC1 | TSHR 4723/4885ALDH1A1 1799/4885CYP3A4 4472/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.