Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 15/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27833622 | 0.98 | ALDH1A1 (0.53) | ALDH1A1NPSR1MAPTJAK2PKM | |
| SCHEMBL958949 | 0.81 | ALDH1A1 (0.56) | ALDH1A1NPSR1MAPTJAK2PKM | |
| SCHEMBL31018073 | 0.81 | ALDH1A1 (0.56) | ALDH1A1NPSR1MAPTJAK2PKM | |
| SCHEMBL27903839 | 0.80 | KDM4E (0.48) | ALDH1A1NPSR1MAPTL3MBTL1POLB | |
| SCHEMBL2650456 | 0.80 | ALDH1A1 (0.59) | ALDH1A1NPSR1MAPTJAK2PKM | |
| SCHEMBL1700033 | 0.79 | ALDH1A1 (0.54) | ALDH1A1NPSR1MAPTJAK2PKM | |
| SCHEMBL30088403 | 0.79 | ALDH1A1 (0.59) | ALDH1A1NPSR1MAPTJAK2PKM | |
| SCHEMBL3716202 | 0.79 | ALDH1A1 (0.59) | ALDH1A1NPSR1MAPTJAK2PKM | |
| SCHEMBL27631188 | 0.79 | KDM4E (0.43) | ALDH1A1NPSR1MAPTLMNAPOLB | |
| Hydrochloric Acid SCHEMBL27600574 | 0.79 | ALDH1A1 (0.58) | ALDH1A1NPSR1MAPTJAK2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102307872-B | BCL-2-selectively apoptosis-inducing agents for the treatment of cancer and immune diseases | ABBVIE 公司 | 2016-06-15 | — | — | CN | disclosed |
| EP-2471363-A1 | Use of aryl-, heteroaryl- and benzylsulfonamide carboxylic acids, -carboxylic acid esters, -carboxylic acid amides and -carbonitriles and/or its salts for increasing stress tolerance in plants | Bayer CropScience AG (DE) | 2012-07-04 | — | — | EP | disclosed |