SCHEMBL10296808

SCHEMBL10296808

O=S(=O)(c1ccc(Oc2c(F)c(F)c(-c3c(F)c(F)c(F)c(F)c3F)c(F)c2F)cc1)c1ccc(Oc2c(F)c(F)c(-c3c(F)c(F)c(F)c(F)c3F)c(F)c2F)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.45
CA1 P00915 2/20 0.45
CA2 P00918 2/20 0.45
CA7 P43166 2/20 0.45
CA13 Q8N1Q1 1/20 0.45
PKM P14618 3/20 0.44
HSD17B10 Q99714 2/20 0.44
HTT P42858 7/20 0.43
SMN1; SMN2 Q16637 4/20 0.43
SOS1 Q07889 2/20 0.42
ALDH1A1 P00352 4/20 0.41
L3MBTL1 Q9Y468 2/20 0.39
TDP1 Q9NUW8 1/20 0.39
POLB P06746 2/20 0.39
MAPT P10636 2/20 0.39
HPGD P15428 1/20 0.39
GAA P10253 1/20 0.38
CA9 Q16790 1/20 0.37
APEX1 P27695 1/20 0.36
CTDSP1 Q9GZU7 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10296806 0.94 CA12 (0.49) CA12CA1CA2CA7CA13
SCHEMBL12780774 0.93 HTT (0.42) CA12CA1CA2CA7CA13
SCHEMBL10296805 0.90 HTT (0.46) CA12CA1CA2CA7CA13
SCHEMBL12770808 0.85 PKM (0.54) CA1CA2PKMHTTSMN1; SMN2
SCHEMBL12341719 0.85 HTT (0.53) CA12CA1CA2CA7CA13
SCHEMBL13953064 0.81 HTT (0.49) PKMHSD17B10HTTSMN1; SMN2ALDH1A1
SCHEMBL13064138 0.80 MAPT (0.40) CA12CA1CA2CA7CA13
SCHEMBL12780786 0.80 PKM (0.49) PKMHTTSMN1; SMN2ALDH1A1L3MBTL1
SCHEMBL13155644 0.79 GAA (0.52) PKMHTTSMN1; SMN2ALDH1A1L3MBTL1
SCHEMBL18883310 0.78 POLB (0.35) CA12CA1CA2CA7CA13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230220158-A1 IONOMERS WITH MACROCYCLIC MOIETIES FOR ION CONDUCTIVITY AND PERMSELECTIVITY NATIONAL SCIENCE FOUNDATION 2023-07-13 US disclosed
US-8211576-B2 aromatic polyether with sulfonic acid-functional block and acid-free blocks; polyether sulfones; polymer electrolyte fuel cells SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-07-03 US disclosed
US-20090117438-A1 POLYMER ELECTROLYTE, AND POLYMER ELECTROLYTE MEMBRANE, MEMBRANE-ELECTRODE ASSEMBLY AND FUEL CELL THAT ARE USING THE POLYMER ELECTROLYTE SUMITOMO CHEMICAL COMPANY , LIMITED (JP) 2009-05-07 US disclosed
US-20070083010-A1 aromatic polyether with sulfonic acid-functional block and acid-free blocks; polyether sulfones; polymer electrolyte fuel cells SUMITOMO CHEMICAL COMPANY, LIMITED 2007-04-12 US disclosed