SCHEMBL1029759

SCHEMBL1029759

C=C(C)C(=O)OC(C)COCCOCC(C)OC(=O)C(=C)C

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.48
THRB P10828 1/20 0.46
ALDH1A1 P00352 2/20 0.38
TDP1 Q9NUW8 1/20 0.37
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
CHRM2 P08172 1/20 0.31
CHRM4 P08173 1/20 0.31
CHRM1 P11229 1/20 0.31
TBXA2R P21731 1/20 0.31
GALR3 O60755 1/20 0.31
MAPT P10636 1/20 0.31
BLM P54132 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31591535 0.93 THRB (0.58) TSHRTHRBALDH1A1TDP1MEN1
SCHEMBL2219398 0.92 TSHR (0.52) TSHRTHRBALDH1A1TDP1CHRM2
SCHEMBL10893401 0.91 THRB (0.56) TSHRTHRBALDH1A1TDP1MEN1
SCHEMBL4063408 0.91 TDP1 (0.50) TSHRTHRBALDH1A1TDP1HSD17B10
SCHEMBL27707717 0.91 TSHR (0.44) TSHRTHRBALDH1A1TDP1
SCHEMBL5984326 0.91 TSHR (0.44) TSHRTHRBALDH1A1TDP1MEN1
SCHEMBL17109947 0.88 TSHR (0.40) TSHRTHRBALDH1A1TDP1MEN1
SCHEMBL12804553 0.88 TSHR (0.40) TSHRTHRBALDH1A1TDP1
SCHEMBL26786230 0.88 TSHR (0.56) TSHRTHRBALDH1A1TDP1
SCHEMBL7191777 0.88 TSHR (0.46) TSHRTHRBALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024108119-A1 ARCHITECTURED POLYMERS AND RELATED METHODS AVERY DENNISON CORPORATION (US) 2024-05-23 WO claimed
WO-2024108119-A1 ARCHITECTURED POLYMERS AND RELATED METHODS AVERY DENNISON CORPORATION (US) 2024-05-23 WO disclosed
US-8592542-B2 Porous resin beads and method of producing nucleic acid using the same NITTO DENKO CORPORATION (JP) 2013-11-26 US disclosed
EP-2138519-B1 Porous resin beads and method of producing nucleic acid using the same NITTO DENKO CORP (JP) 2011-01-19 EP disclosed
US-20090326210-A1 POROUS RESIN BEADS AND METHOD OF PRODUCING NUCLEIC ACID USING THE SAME NITTO DENKO CORPORATION (JP) 2009-12-31 US disclosed
EP-2138519-A1 Porous resin beads and method of producing nucleic acid using the same Nitto Denko Corporation (JP) 2009-12-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090326210-A1 POROUS RESIN BEADS AND METHOD OF PRODUCING NUCLEIC ACID USING THE SAME PCNA, ARID2, PHAX TSHR 4117/4885THRB 3783/4885ALDH1A1 2929/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.