SCHEMBL10299367

SCHEMBL10299367

COC(=O)COc1nc(N)c2nc(C)n(Cc3ccccc3)c2n1

nearest known ligand 0.56

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 20/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2060210 0.89 TLR7 (0.56) TLR7
SCHEMBL2060194 0.88 TLR7 (0.55) TLR7
SCHEMBL10260765 0.82 TLR7 (0.76) TLR7
SCHEMBL2060080 0.82 PDE4A (0.53) TLR7
SCHEMBL2060784 0.81 TLR7 (0.54) TLR7
SCHEMBL10174481 0.78 TLR7 (0.52) TLR7
SCHEMBL2060157 0.74 TLR7 (0.56) TLR7
SCHEMBL15996369 0.74 TLR7 (0.58) TLR7
SCHEMBL12726790 0.73 TLR7 (0.78) TLR7
SCHEMBL10292185 0.73 TLR7 (0.68) TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1550662-B1 ADENINE COMPOUND AND USE THEREOF DAINIPPON SUMITOMO PHARMA CO (JP) 2012-07-04 EP disclosed