⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13377432 | 0.79 | — | — | |
| SCHEMBL17732693 | 0.78 | — | — | |
| SCHEMBL11919370 | 0.78 | — | — | |
| SCHEMBL14382433 | 0.77 | — | — | |
| SCHEMBL9480208 | 0.76 | — | — | |
| SCHEMBL12744997 | 0.76 | ALDH1A1 (0.41) | — | |
| SCHEMBL19771799 | 0.74 | — | — | |
| SCHEMBL21139376 | 0.73 | ALDH1A1 (0.38) | — | |
| SCHEMBL15684690 | 0.73 | TSHR (0.41) | — | |
| SCHEMBL28898892 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340691-A1 | COMBINATION OF PHOTOINITIATORS AND USES THEREOF | IGM RESINS ITALIA S.R.L. (IT) | 2022-10-27 | — | — | US | disclosed |
| US-20210284987-A1 | ENGINEERED POLYPEPTIDES AND THEIR APPLICATIONS IN THE SYNTHESIS OF BETA-HYDROXY-ALPHA-AMINO ACIDS | ENZYMASTER (NINGBO) BIO-ENGINEERING CO., LTD. (CN) | 2021-09-16 | — | — | US | disclosed |
| EP-3634943-B1 | METHOD FOR PREPARATION OF DIFLUOROMETHYLORNITHINE | LONZA AG (CH) | 2020-09-09 | — | — | EP | disclosed |
| US-20200131139-A1 | SMALL MOLECULE INHIBITORS OF BCL-2- ASSOCIATED DEATH PROMOTER (BAD) PHOSPHORYLATION | BANGALORE UNIVERSITY (IN) | 2020-04-30 | — | — | US | disclosed |
| US-20200123525-A1 | ENGINEERED ALDOLASE POLYPEPTIDES AND USES THEREOF | Enzymaster (Ningbo) Bio-Engineering Co., Ltd (CN) | 2020-04-23 | — | — | US | disclosed |
| WO-2019057951-A1 | METHOD FOR PREPARATION OF DIFLUOROMETHYLORNITHINE | LONZA LTD (CH) | 2019-03-28 | — | — | WO | disclosed |
| US-9951034-B2 | 3-ketocoumarines for LED photocuring | IGM RESINS ITALIA S.R.L. (IT) | 2018-04-24 | — | — | US | disclosed |
| US-9701637-B2 | Tau imaging probe | GE HEALTHCARE LIMITED (GB) | 2017-07-11 | — | — | US | disclosed |
| US-20170036981-A1 | PROCESS FOR PREPARING ARYL KETONE | ETERNAL MATERIALS CO., LTD. (TW) | 2017-02-09 | — | — | US | disclosed |
| US-8222423-B2 | Bifunctional histone deacetylase inhibitors | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2012-07-17 | — | — | US | disclosed |
| US-20120171379-A1 | RADIATION-SENSITIVE COMPOSITION | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2012-07-05 | — | — | US | disclosed |
| US-20090312363-A1 | BIFUNCTIONAL HISTONE DEACETYLASE INHIBITORS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2009-12-17 | — | — | US | disclosed |
| US-7371411-B2 | Methods for production of the oxidized glutathione composite with CIS-diamminedichloroplatinum and pharmaceutical compositions based thereof regulating metabolism, proliferation, differentiation and apoptotic mechanisms for normal and transformed cells | NOVELOS THERAPEUTICS, INC. (US) | 2008-05-13 | — | — | US | disclosed |