Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | DPP4 | P27487 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10174670 | 0.86 | DPP4 (0.33) | SMN1; SMN2DPP4HSP90AA1 | |
| SCHEMBL6587454 | 0.80 | SMN1; SMN2 (0.43) | SMN1; SMN2DPP4ALDH1A1RECQLCA12 | |
| SCHEMBL12298619 | 0.80 | SMN1; SMN2 (0.43) | SMN1; SMN2DPP4ALDH1A1RECQLCA12 | |
| SCHEMBL20459309 | 0.80 | SMN1; SMN2 (0.45) | SMN1; SMN2DPP4ALDH1A1CA12CA1 | |
| SCHEMBL907575 | 0.77 | SMN1; SMN2 (0.43) | SMN1; SMN2DPP4ALDH1A1CA12CA1 | |
| SCHEMBL14291273 | 0.75 | CYP17A1 (0.31) | — | |
| SCHEMBL12478230 | 0.74 | SMN1; SMN2 (0.40) | SMN1; SMN2DPP4ALDH1A1CA12CA1 | |
| SCHEMBL29104397 | 0.72 | CA12 (0.50) | SMN1; SMN2ALDH1A1CA12CA1CA2 | |
| SCHEMBL5780912 | 0.72 | PDK1 (0.30) | — | |
| SCHEMBL8863393 | 0.72 | SMN1; SMN2 (0.46) | SMN1; SMN2CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1550662-B1 | ADENINE COMPOUND AND USE THEREOF | DAINIPPON SUMITOMO PHARMA CO (JP) | 2012-07-04 | — | — | EP | disclosed |