Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 15/20 | 0.65 |
| ▸ | RAB9A | P51151 | 15/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.65 |
| ▸ | TSHR | P16473 | 5/20 | 0.62 |
| ▸ | HPGD | P15428 | 4/20 | 0.62 |
| ▸ | TP53 | P04637 | 2/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.62 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.62 |
| ▸ | RELA | Q04206 | 2/20 | 0.62 |
| ▸ | MECP2 | P51608 | 1/20 | 0.62 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.54 |
| ▸ | GUSB | P08236 | 1/20 | 0.53 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.53 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1180155 | 0.94 | HSD17B1 (0.59) | NPC1RAB9ASMN1; SMN2TSHRHPGD | |
| SCHEMBL11939392 | 0.86 | GUSB (0.52) | NPC1RAB9ASMN1; SMN2TSHRHPGD | |
| SCHEMBL14378791 | 0.86 | NPC1 (0.81) | NPC1RAB9ASMN1; SMN2TSHRHPGD | |
| SCHEMBL12171406 | 0.85 | NPC1 (0.73) | NPC1RAB9ASMN1; SMN2TSHRHPGD | |
| SCHEMBL29090805 | 0.84 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2TSHRHPGD | |
| SCHEMBL5638741 | 0.84 | NPC1 (0.59) | NPC1RAB9ASMN1; SMN2TSHRHPGD | |
| SCHEMBL12306757 | 0.84 | NPC1 (0.77) | NPC1RAB9ASMN1; SMN2TSHRHPGD | |
| SCHEMBL12171741 | 0.83 | CA12 (0.58) | NPC1RAB9ASMN1; SMN2TSHRHPGD | |
| SCHEMBL9737591 | 0.82 | NPC1 (0.58) | NPC1RAB9ASMN1; SMN2TSHRHPGD | |
| SCHEMBL967890 | 0.82 | NPC1 (0.54) | NPC1RAB9ASMN1; SMN2TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120168732-A1 | AMBIPOLAR SMALL MOLECULE HOSTS FOR PHOSPHORESCENT GUEST EMITTERS | GEORGIA TECH RESEARCH CORPORATION (US) | 2012-07-05 | — | — | US | disclosed |
| US-20120172556-A1 | POLYMERIZABLE AMBIPOLAR HOSTS FOR PHOSPHORESCENT GUEST EMITTERS | GEORGIA TECH RESEARCH CORPORATION | 2012-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120172556-A1 | POLYMERIZABLE AMBIPOLAR HOSTS FOR PHOSPHORESCENT GUEST EMITTERS | OCIAD1, OCIAD2, OXA1L | NPC1 643/4885RAB9A 2633/4885SMN1; SMN2 4701/4885 |
| US-20120168732-A1 | AMBIPOLAR SMALL MOLECULE HOSTS FOR PHOSPHORESCENT GUEST EMITTERS | OCIAD2, OCIAD1, ORC3 | NPC1 816/4885RAB9A 1811/4885SMN1; SMN2 4781/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.