Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 10/20 | 0.38 |
| ▸ | CCR9 | P51686 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
| ▸ | TKT | P29401 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2060420 | 0.91 | TLR7 (0.40) | TLR7CCR9ADORA1ADORA2AP2RX3 | |
| SCHEMBL2060315 | 0.90 | ADORA2A (0.38) | TLR7CCR9ADORA1ADORA2AP2RX3 | |
| SCHEMBL2060257 | 0.85 | CYP11B1 (0.41) | CYP11B1CYP11B2 | |
| SCHEMBL10174470 | 0.80 | TSHR (0.40) | TLR7ADORA1ADORA2ATSHRSMN1; SMN2 | |
| SCHEMBL2060146 | 0.78 | TLR7 (0.42) | TLR7ADORA1ADORA2ACYP11B1CYP11B2 | |
| SCHEMBL2060646 | 0.76 | TLR7 (0.48) | TLR7ADORA1ADORA2ACYP11B1CYP11B2 | |
| SCHEMBL2060250 | 0.73 | TLR7 (0.46) | TLR7ADORA1ADORA2A | |
| SCHEMBL5464032 | 0.73 | TLR7 (0.47) | TLR7 | |
| SCHEMBL10309723 | 0.72 | ADORA2A (0.44) | TLR7ADORA1ADORA2A | |
| SCHEMBL4734773 | 0.72 | TSHR (0.51) | CCR9CYP11B1CYP11B2TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1550662-B1 | ADENINE COMPOUND AND USE THEREOF | DAINIPPON SUMITOMO PHARMA CO (JP) | 2012-07-04 | — | — | EP | disclosed |