⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL28778977 | 0.91 | SMN1; SMN2 (0.42) | — | |
| SCHEMBL279148 | 0.80 | SMN1; SMN2 (0.48) | — | |
| Hydrochloric Acid SCHEMBL655143 | 0.78 | SMN1; SMN2 (0.46) | — | |
| SCHEMBL16081670 | 0.78 | — | — | |
| SCHEMBL10151193 | 0.78 | — | — | |
| SCHEMBL41892 | 0.78 | — | — | |
| SCHEMBL30039818 | 0.78 | — | — | |
| SCHEMBL104803 | 0.78 | — | — | |
| SCHEMBL72838 | 0.78 | — | — | |
| SCHEMBL25301326 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4209498-A1 | 4'-THIO-NUCLEOTIDE AND -NUCLEOSIDE PRODRUGS FOR THE TREATMENT OF CANCER | Southern Research Institute (US) | 2023-07-12 | — | — | EP | disclosed |
| US-20230133817-A1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX PHARMACEUTICALS INC (US) | 2023-05-04 | — | — | US | disclosed |
| US-20210198316-A9 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | CHARLES RIVER DISCOVERY RESEARCH SERVICES UK LIMITED (GB) | 2021-07-01 | — | — | US | disclosed |
| WO-2017114382-A1 | METHOD FOR SYNTHESIZING C-TERMINAL MODIFIED PEPTIDE | 深圳翰宇药业股份有限公司 | 2017-07-06 | — | — | WO | disclosed |
| US-8217031-B2 | Heteroaryl derivatives | NIPPON SHINYAKU CO., LTD. (JP) | 2012-07-10 | — | — | US | disclosed |
| US-20100048537-A1 | HETEROARYL DERIVATIVES | NIPPON SHINYAKU CO., LTD. (JP) | 2010-02-25 | — | — | US | disclosed |