Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 3/20 | 0.46 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | TKT | P29401 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 5/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 5/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13373481 | 0.84 | DAO (0.45) | DAOTRPV4KCNH2MAP4K4PIK3CA | |
| SCHEMBL12464108 | 0.82 | DAO (0.44) | DAOTRPV4KCNH2MAP4K4PIK3CA | |
| SCHEMBL2152745 | 0.78 | DAO (0.41) | DAOTRPV4KCNH2MAP4K4PIK3CA | |
| SCHEMBL24008850 | 0.78 | TSHR (0.45) | KCNH2HTR2ANAMPTPTGS2 | |
| SCHEMBL15541648 | 0.77 | DAO (0.40) | DAOTRPV4KCNH2MAP4K4PIK3CA | |
| SCHEMBL22775173 | 0.77 | CA2 (0.42) | DAOTRPV4KCNH2MAP4K4PIK3CA | |
| SCHEMBL3642938 | 0.76 | DAO (0.39) | DAOTRPV4KCNH2MAP4K4PIK3CA | |
| SCHEMBL3641928 | 0.76 | DAO (0.37) | DAOKCNH2PIK3CAPI4KBHTR2A | |
| SCHEMBL30469149 | 0.75 | DAO (0.43) | DAOTRPV4KCNH2MAP4K4PIK3CA | |
| SCHEMBL25214525 | 0.75 | DAO (0.43) | DAOTRPV4KCNH2MAP4K4PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2369921-A1 | STABLE SULFOXIMINE-INSECTICIDE COMPOSITIONS | Dow AgroSciences LLC (US) | 2011-10-05 | — | — | EP | disclosed |
| EP-2369935-A1 | STABLE INSECTICIDE COMPOSITIONS AND METHODS FOR PRODUCING SAME | Dow AgroSciences LLC (US) | 2011-10-05 | — | — | EP | disclosed |
| EP-2268615-A1 | PESTICIDES | Dow AgroSciences LLC (US) | 2011-01-05 | — | — | EP | disclosed |
| WO-2010074751-A1 | STABLE SULFOXIMINE-INSECTICIDE COMPOSITIONS | DOW AGROSCIENCES, LLC (US) | 2010-07-01 | — | — | WO | disclosed |
| WO-2010074747-A1 | STABLE INSECTICIDE COMPOSITIONS AND METHODS FOR PRODUCING SAME | DOW AGROSCIENCES, LLC (US) | 2010-07-01 | — | — | WO | disclosed |
| EP-2170066-A2 | PESTICIDES AND USES THEREOF | Dow AgroSciences LLC (US) | 2010-04-07 | — | — | EP | disclosed |
| EP-2166851-A2 | INCREASING PLANT VIGOR | Dow AgroSciences LLC (US) | 2010-03-31 | — | — | EP | disclosed |
| WO-2009111309-A1 | PESTICIDES | DOW AGROSCIENCES LLC (US) | 2009-09-11 | — | — | WO | disclosed |
| WO-2009017951-A2 | PESTICIDES AND USES THEREOF | DOW AGROSCIENCES LLC (US) | 2009-02-05 | — | — | WO | disclosed |
| WO-2009014891-A2 | INCREASING PLANT VIGOR | DOW AGROSCIENCES LLC (US) | 2009-01-29 | — | — | WO | disclosed |
| EP-1989184-A2 | INSECTICIDAL N-SUBSTITUTED (6-HALOALKYLPYRIDIN-3-YL)ALKYL SULFOXIMINES | Dow AgroSciences LLC (US) | 2008-11-12 | — | — | EP | disclosed |
| WO-2007095229-A2 | INSECTICIDAL N-SUBSTITUTED (6-HALOALKYLPYRIDIN-3-YL)ALKYL SULFOXIMINES | DOW AGROSCIENCES LLC (US) | 2007-08-23 | — | — | WO | disclosed |