SCHEMBL10300993

SCHEMBL10300993

c1ccc(-c2cc(-c3ccc4c(-c5ccccc5)c5cc(-c6ccc7c(c6)C6(CCCCC6)c6ccccc6-7)ccc5c(-c5ccccc5)c4c3)cc(-c3ccccc3)n2)cc1

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 10/20 0.37
PGR P06401 2/20 0.36
KDM4E B2RXH2 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ADORA3 P0DMS8 2/20 0.33
ADORA2B P29275 2/20 0.33
ADORA1 P30542 2/20 0.33
HTT P42858 2/20 0.33
HSD17B10 Q99714 2/20 0.33
ADORA2A P29274 1/20 0.33
HPGD P15428 1/20 0.32
PDE7A Q13946 1/20 0.32
USP2 O75604 1/20 0.31
LMNA P02545 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10301010 0.99 PDK2 (0.38) PDK2PGRKDM4EL3MBTL1ADORA3
SCHEMBL10300997 0.97 PDK2 (0.36) PDK2PGRKDM4EL3MBTL1ADORA3
SCHEMBL10301005 0.95 PDK2 (0.37) PDK2PGRKDM4EL3MBTL1ADORA3
SCHEMBL10301022 0.92 HPGD (0.36) PDK2PGRKDM4EL3MBTL1ADORA3
SCHEMBL10301079 0.91 HPGD (0.38) PDK2PGRKDM4EL3MBTL1ADORA3
SCHEMBL10300919 0.91 PDK2 (0.37) PDK2PGR
SCHEMBL10301036 0.91 HPGD (0.36) PDK2PGRKDM4EL3MBTL1ADORA3
SCHEMBL10301078 0.90 MEN1 (0.38) PDK2PGRKDM4EADORA3ADORA1
SCHEMBL10301154 0.89 PGR (0.36) PDK2PGRADORA1ADORA2AHPGD
SCHEMBL10301045 0.88 HPGD (0.36) PDK2PGRKDM4EL3MBTL1ADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8217570-B2 Anthracene derivative and organic electroluminescent element using the same IDEMITSU KOSAN CO., LTD. (JP) 2012-07-10 US disclosed
US-8217570-B2 Anthracene derivative and organic electroluminescent element using the same IDEMITSU KOSAN CO., LTD. (JP) 2012-07-10 US disclosed
US-20080111473-A1 Anthracene Derivative and Organic Electroluminescent Element Using the Same IDEMITSU KOSAN CO., LTD. (JP) 2008-05-15 US disclosed
US-20080111473-A1 Anthracene Derivative and Organic Electroluminescent Element Using the Same IDEMITSU KOSAN CO., LTD. (JP) 2008-05-15 US disclosed