SCHEMBL10302

SCHEMBL10302

Nc1ccc(C(F)(F)F)cc1

nearest known ligand 0.84

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 5/20 0.84
MAOB P27338 3/20 0.57
PTGS1 P23219 2/20 0.55
TAAR1 Q96RJ0 1/20 0.54
TSHR P16473 2/20 0.50
ALDH1A1 P00352 2/20 0.50
MEN1 O00255 1/20 0.50
MAPT P10636 1/20 0.50
KMT2A Q03164 1/20 0.50
MAPK1 P28482 1/20 0.50
HTR3E A5X5Y0 1/20 0.46
HTR3B O95264 1/20 0.46
PLAU P00749 1/20 0.46
HTR3A P46098 1/20 0.46
HTR3D Q70Z44 1/20 0.46
HTR3C Q8WXA8 1/20 0.46
IDO1 P14902 1/20 0.46
CES2 O00748 1/20 0.46
CES1 P23141 1/20 0.46
KDM4E B2RXH2 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27948267 1.00 KIF11 (0.84) KIF11MAOBPTGS1TAAR1TSHR
SCHEMBL30438832 1.00 KIF11 (0.84) KIF11MAOBPTGS1TAAR1TSHR
SCHEMBL7267368 0.97 KIF11 (0.80) KIF11MAOBPTGS1TAAR1TSHR
Bromide SCHEMBL29203653 0.97 KIF11 (0.80) KIF11MAOBPTGS1TAAR1TSHR
Fluoride SCHEMBL10884506 0.97 KIF11 (0.80) KIF11MAOBPTGS1TAAR1TSHR
Iodide SCHEMBL29168424 0.97 KIF11 (0.80) KIF11MAOBPTGS1TAAR1TSHR
SCHEMBL11737429 0.97 KIF11 (0.80) KIF11MAOBPTGS1TAAR1TSHR
Hydrochloric Acid SCHEMBL4376065 0.97 KIF11 (0.80) KIF11MAOBPTGS1TAAR1TSHR
Hydrochloric Acid SCHEMBL2130181 0.97 KIF11 (0.80) KIF11MAOBPTGS1TAAR1TSHR
Ammonia Solution, Strong SCHEMBL27928518 0.97 KIF11 (0.80) KIF11MAOBPTGS1TAAR1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 7273 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122038010-A Lubricating grease composition with excellent heat resistance stability, and preparation method and application thereof 思潞博(河南)新材料有限公司 2026-05-15 CN claimed
CN-116053577-B Polyurea and polythiourea super-ion solid electrolyte and preparation method and application thereof 华南理工大学 2026-05-12 CN claimed
EP-4724442-A1 AGONISM-ANTAGONISM IN ENDOSOMAL TLRS BY MODULATING CHEMICAL FEATURES IN 8-OXOPURINE: PROCESS FOR PREPARATION AND APPLICATION THEREOF Council of Scientific and Industrial Research (IN) 2026-04-15 EP claimed
CN-119912852-B Flame-retardant acrylic ester emulsion for water-based paint and preparation method thereof 佛山罗斯夫科技有限公司 2025-06-24 CN claimed
CN-120040308-A Triphenylamine organic small molecular compound, preparation method and application thereof in perovskite solar cell 江苏科技大学 2025-05-27 CN claimed
CN-119391365-B Heat-conducting pouring sealant material and preparation method thereof 东莞市跨越电子有限公司 2025-05-06 CN claimed
CN-119912852-A Flame-retardant acrylic ester emulsion for water-based paint and preparation method thereof 佛山罗斯夫科技有限公司 2025-05-02 CN claimed
CN-119899184-A Beta-carboline compound, preparation method thereof and application thereof in resisting Alzheimer disease 中国人民解放军北部战区总医院 2025-04-29 CN claimed
CN-119286106-B Antibacterial plastic and production process thereof 东莞市新伦塑胶科技有限公司 2025-04-29 CN claimed
CN-119874598-A Indole-3-acetamide derivative and preparation method and application thereof 河北农业大学 2025-04-25 CN claimed
EP-0060171-B1 PROCESS FOR THE N-ALKYLATION OF ORGANIC NITROGEN COMPOUNDS RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1985-05-15 EP claimed
US-4481370-A REACTING HYDROGEN FLUORIDE WITH A PHENYL CARBAMIC FLUORIDE OCCIDENTAL CHEMICAL CORPORATION (US) 1984-11-06 US claimed
US-4417048-A N-alkylation of organonitrogen compounds RHONE-POULENC SPECIALTIES CHIMIQUES (FR) 1983-11-22 US claimed
EP-0060171-A1 Process for the N-alkylation of organic nitrogen compounds RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1982-09-15 EP claimed
EP-0013376-B1 ISOXAZOLE DERIVATIVE, PROCESS FOR ITS PREPARATION AND COMPOSITION CONTAINING IT HOECHST AKTIENGESELLSCHAFT (DE) 1982-05-19 EP claimed
EP-0003430-B1 NOVEL 2,6-DINITROBENZENAMINES, THEIR PREPARATION, COMPOSITION CONTAINING THEM AND THEIR USE AS FUNGICIDES ELI LILLY AND COMPANY (US) 1982-01-06 EP claimed
US-4261926-A REACTION WITH KETONE IN PRESENCE OF PLATINUM HYDROGENATION CATALYST AND A PROMOTER ACID AMERICAN CYANAMID COMPANY (US) 1981-04-14 US claimed
EP-0013376-A2 Isoxazole derivative, process for its preparation and composition containing it HOECHST AKTIENGESELLSCHAFT (DE) 1980-07-23 EP claimed
US-4096185-A P-CHLOROBENZOTRIFLUORIDE, AMMONIA, COPPER COMPOUND CATALYST E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-06-20 US claimed
US-4064129-A Process for making quinacridone and its derivatives HARMON COLORS CORPORATION (US) 1977-12-20 US claimed