Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 6/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.45 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.45 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.45 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14283018 | 1.00 | PIK3CD (0.45) | PIK3CDPIK3CAPIK3CBPIK3CGUCHL1 | |
| SCHEMBL14283026 | 0.90 | PIK3CD (0.47) | PIK3CDPIK3CAPIK3CBPIK3CGUCHL1 | |
| SCHEMBL10304592 | 0.90 | PIK3CD (0.47) | PIK3CDPIK3CAPIK3CBPIK3CGUCHL1 | |
| SCHEMBL13385341 | 0.86 | PIK3CD (0.46) | PIK3CDPIK3CAPIK3CBPIK3CGUCHL1 | |
| SCHEMBL2151292 | 0.86 | UCHL1 (0.44) | UCHL1MCL1 | |
| SCHEMBL2151286 | 0.86 | UCHL1 (0.44) | UCHL1MCL1 | |
| SCHEMBL7866789 | 0.84 | HCRTR1 (0.47) | PIK3CDUCHL1MCL1 | |
| SCHEMBL16470955 | 0.84 | HCRTR1 (0.47) | PIK3CDUCHL1MCL1 | |
| SCHEMBL374720 | 0.84 | HCRTR1 (0.47) | PIK3CDUCHL1MCL1 | |
| SCHEMBL14586202 | 0.84 | HCRTR1 (0.47) | PIK3CDUCHL1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863793-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2012-07-04 | — | — | EP | disclosed |
| US-7323447-B2 | Hepatitis C virus inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-01-29 | — | — | US | disclosed |