UCHL1 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL460676	0.49	11/20
SCHEMBL460677	0.49	11/20
SCHEMBL460678	0.49	11/20
SCHEMBL1271972	0.53	9/20
SCHEMBL834021	0.64	7/20
SCHEMBL77860	0.60	7/20
SCHEMBL382918	0.49	7/20
SCHEMBL382919	0.49	7/20
SCHEMBL256730	0.53	6/20
SCHEMBL1523718	0.51	6/20
SCHEMBL650608	0.39	6/20
SCHEMBL1284259	0.67	5/20
SCHEMBL1255720	0.51	5/20
SCHEMBL648932	0.45	5/20
SCHEMBL651231	0.42	5/20
SCHEMBL651232	0.42	5/20
SCHEMBL653151	0.41	5/20
SCHEMBL653287	0.40	5/20
SCHEMBL256728	0.51	4/20
SCHEMBL868725	0.51	4/20

Clinical trials — most relevant to UCHL1 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Blood-Based Molecular Clock Biomarkers Predict Acute Ischemic Stroke Onset: A Prospective Observational Study	nan	ACTIVE_NOT_RECRUITING
Evaluation of Biomarker Kinetics After Mild Brain Injury Trauma	nan	COMPLETED
Cerebrolysin in Prevention of Postoperative Delirium in Cardiac Surgery	nan	UNKNOWN
Systemic Biomarkers of Brain Injury From Hyperammonemia	nan	RECRUITING
Safety of Transcutaneous Electrical Stimulation Potentiating Recovery in Acute Spinal Cord Injury Syndromes	nan	RECRUITING
Diagnostic Potential of UCHL1 in Acute Decompensated Heart Failure	nan	COMPLETED
Prognostic Biomarkers in Tumor Tissue Samples From Young Patients With Neuroblastoma	nan	COMPLETED
Neuronal Damage In Delirium Study	nan	COMPLETED
Glial Fibrillary Acidic Protein (GFAP) and Ubiquitin Carboxy-terminal Hydrolase L1 (UCH-L1) to Exclude Lesions Linked to Significant Traumatic Brain Injuries	nan	RECRUITING
Neuronal and Glial Biomarkers in Stroke	nan	COMPLETED
Cerebral Protection in Aortic Arch Surgery	nan	ACTIVE_NOT_RECRUITING
Impact of Photobiomodulation (PBM) on Biomarkers of Alzheimer's Disease	nan	COMPLETED
Rapid, Accurate, Cost-effective Assessment of Blood Biomarkers for Diagnosis of Concussion	nan	RECRUITING
Systemic Nitrosative/Oxidative Stress in Patients with Acute Brain Injury	nan	UNKNOWN
BRIDGE-US: Bridging Readiness in Deployed Neurotrauma Gaps for Excellence	nan	NOT_YET_RECRUITING
Blood-based Biomarkers for the Prognosis of Sports Related Concussion	nan	COMPLETED
VIDAS® TBI Real Life Performance in Subjects With Mild Traumatic Brain Injury (mTBI)	nan	COMPLETED
Single-center Transversal Observational Study on the Evaluation of S100B Changes in Subjects Attending the Emergency Department With Head Trauma	nan	RECRUITING
Prediction of Delayed Cognitive Impairment in Cardiac Arrest Survivors With Good Neurological Outcomes	nan	ENROLLING_BY_INVITATION
Using Routine Inflammatory and Metabolic Blood Tests (Bedside Included) to Predict Brain Injury in Children After Minor Head Trauma	nan	NOT_YET_RECRUITING
Validating a Blood Test for the Detection of Traumatic Brain Injury in Children	nan	RECRUITING
Use of Cerebral Biomarkers in Minor Traumatic Brain Injury in the Emergency Unit	nan	UNKNOWN
Usefulness of Biomarkers in the Management of Mild Traumatic Brain Injury in Adults (Biotraumap)	nan	COMPLETED
A Study of Biomarkers of Mild Traumatic BRAIN Injury	nan	COMPLETED
BRAINI-2 Elderly Mild TBI European Study	nan	COMPLETED
Early Detection of Brain Injury After Congenital Heart Surgery in Infants	nan	ENROLLING_BY_INVITATION
A Patient-tailored Genetic/Biomarker/iPSC Combined Approach in ALS - PERMEALS	nan	RECRUITING
Hemodynamic Instability of Patient With Spontaneous Subarachnoid Hemorrhage	nan	RECRUITING
Implementation of Biomarker-Based Care for mTBI - IMPACTS-BRAINI Study	nan	RECRUITING
Transforming Research and Clinical Knowledge in TBI Pilot	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a UCHL1 binder may also engage these)

Protein	Name	Similarity
Q60HC8	—	1.000	Q60HC8 →
Q6SEG5	—	1.000	Q6SEG5 →
Q9GM50	—	1.000	Q9GM50 →
Q00981	—	0.999	Q00981 →
Q9R0P9	—	0.999	Q9R0P9 →
P50103	—	0.979	P50103 →
Q2TBG8	—	0.970	Q2TBG8 →
Q91Y78	—	0.968	Q91Y78 →
Q9JKB1	—	0.967	Q9JKB1 →
UCHL3	Ubiquitin carboxyl-terminal hydrolase isozyme L3	0.963	landscape →
Q06AB3	—	0.957	Q06AB3 →
P23356	—	0.957	P23356 →
O04482	—	0.946	O04482 →
Q9WUP7	—	0.939	Q9WUP7 →
Q9XSJ0	—	0.936	Q9XSJ0 →
UCHL5	Ubiquitin carboxyl-terminal hydrolase isozyme L5	0.927	landscape →
Q06AT3	—	0.925	Q06AT3 →
Q8GWE1	—	0.921	Q8GWE1 →
Q28DS0	—	0.920	Q28DS0 →
P87362	—	0.918	P87362 →
Q5F3A6	—	0.917	Q5F3A6 →
Q2QZ86	—	0.917	Q2QZ86 →
Q9BUP3	—	0.916	Q9BUP3 →
A1YFX9	—	0.916	A1YFX9 →
Q5E964	—	0.914	Q5E964 →
Q8R127	—	0.913	Q8R127 →
A0FKG7	—	0.913	A0FKG7 →
A1YER2	—	0.912	A1YER2 →
Q2QNG7	—	0.912	Q2QNG7 →
A2T7G9	—	0.912	A2T7G9 →