Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 12/20 | 0.62 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.46 |
| ▸ | KIT | P10721 | 2/20 | 0.42 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | AKT2 | P31751 | 1/20 | 0.42 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1030271 | 0.82 | PDGFRB (0.56) | PDGFRBACHEBACE1MTNR1BKIT | |
| SCHEMBL1032708 | 0.78 | PDGFRB (1.00) | PDGFRBKITPDGFRA | |
| SCHEMBL16637012 | 0.76 | PDGFRB (0.52) | PDGFRBACHEBACE1KITPDGFRA | |
| SCHEMBL16637014 | 0.76 | PDGFRB (0.52) | PDGFRBACHEBACE1KITPDGFRA | |
| SCHEMBL16637875 | 0.74 | PDGFRB (0.49) | PDGFRBACHEBACE1KITENPP1 | |
| SCHEMBL21839989 | 0.74 | PDGFRB (0.49) | PDGFRBACHEBACE1KITPDGFRA | |
| Hydrochloric Acid SCHEMBL2915718 | 0.74 | ACHE (0.80) | PDGFRBACHEBACE1KITENPP1 | |
| SCHEMBL16637244 | 0.74 | KRAS (0.52) | PDGFRBACHEBACE1 | |
| SCHEMBL16637441 | 0.73 | CYP3A4 (0.51) | PDGFRBKITAKT1AKT2AKT3 | |
| SCHEMBL22631342 | 0.73 | ACHE (0.53) | PDGFRBACHEBACE1MTNR1BKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111989321-B | KRAS G12C inhibitors | 米拉蒂治疗股份有限公司 | 2024-05-14 | — | — | CN | disclosed |
| EP-1067123-B1 | NITROGENOUS HETEROCYCLIC COMPOUNDS | KYOWA HAKKO KIRIN CO LTD (JP) | 2011-01-19 | — | — | EP | disclosed |