Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | NTRK1 | P04629 | 4/20 | 0.44 |
| ▸ | IGF1R | P08069 | 3/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.43 |
| ▸ | KDR | P35968 | 3/20 | 0.43 |
| ▸ | INSR | P06213 | 1/20 | 0.43 |
| ▸ | VNN1 | O95497 | 2/20 | 0.42 |
| ▸ | PAK4 | O96013 | 5/20 | 0.41 |
| ▸ | PLK4 | O00444 | 4/20 | 0.41 |
| ▸ | NTRK3 | Q16288 | 2/20 | 0.41 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10312224 | 0.91 | NTRK1 (0.50) | NTRK1IGF1RFGFR1KDRINSR | |
| SCHEMBL10312129 | 0.90 | KDM4E (0.41) | KDM4EHSD17B10IGF1RFGFR1KDR | |
| SCHEMBL10312189 | 0.89 | PAK4 (0.51) | KDM4EHSD17B10NTRK1IGF1RFGFR1 | |
| SCHEMBL10312109 | 0.87 | PLK4 (0.50) | NTRK1IGF1RFGFR1KDRINSR | |
| SCHEMBL10312186 | 0.87 | IGF1R (0.53) | KDM4EHSD17B10NTRK1IGF1RFGFR1 | |
| SCHEMBL10312055 | 0.82 | KDM4E (0.44) | KDM4EHSD17B10KDRVNN1DDR1 | |
| SCHEMBL10312133 | 0.80 | NTRK1 (0.39) | NTRK1IGF1RKDRVNN1DAPK3 | |
| SCHEMBL10312078 | 0.80 | DHODH (0.41) | NTRK1FGFR1KDRINSRPAK4 | |
| SCHEMBL10312181 | 0.79 | IDH2 (0.48) | NTRK1IGF1RFGFR1KDRINSR | |
| SCHEMBL10312195 | 0.79 | PAK4 (0.48) | NTRK1IGF1RFGFR1KDRPAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440055-B1 | STYRYL-TRIAZINE DERIVATIVES AND THEIR THERAPEUTICAL APPLICATIONS | CALIFORNIA CAPITAL EQUITY LLC (US) | 2015-03-11 | — | — | EP | disclosed |
| US-20120178758-A1 | STYRYL-TRIAZINE DERIVATIVES AND THEIR THERAPEUTICAL APPLICATIONS | CALIFORNIA CAPITAL EQUITY, LLC (US) | 2012-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120178758-A1 | STYRYL-TRIAZINE DERIVATIVES AND THEIR THERAPEUTICAL APPLICATIONS | STK25, STK35, SGK2 | KDM4E 2463/4885HSD17B10 3171/4885NTRK1 482/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.