SCHEMBL10312481

SCHEMBL10312481

NCCNC1CC2CCC1C2

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 4/20 0.44
SIGMAR1 Q99720 4/20 0.43
GRIN2D O15399 2/20 0.43
GRIN3B O60391 2/20 0.43
GRIN1 Q05586 2/20 0.43
GRIN2A Q12879 2/20 0.43
GRIN2B Q13224 2/20 0.43
GRIN2C Q14957 2/20 0.43
GRIN3A Q8TCU5 2/20 0.43
EPHX1 P07099 1/20 0.43
DPP4 P27487 2/20 0.40
MAPT P10636 1/20 0.40
POLB P06746 1/20 0.36
ALDH1A1 P00352 2/20 0.35
TAS1R3 Q7RTX0 1/20 0.35
TAS1R1 Q7RTX1 1/20 0.35
TAS1R2 Q8TE23 1/20 0.35
GAA P10253 1/20 0.34
TDP1 Q9NUW8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8040794 0.79 EPHX2 (0.44) EPHX2SIGMAR1GRIN2DGRIN3BGRIN1
SCHEMBL22744300 0.78 EPHX2 (0.36) EPHX2SIGMAR1GRIN2DGRIN3BGRIN1
SCHEMBL30142448 0.76 EPHX2 (0.46) EPHX2SIGMAR1GRIN2DGRIN3BGRIN1
SCHEMBL8357133 0.74 MAPT (0.46) EPHX2SIGMAR1GRIN2DGRIN3BGRIN1
SCHEMBL1786896 0.74 EPHX2 (0.43) EPHX2SIGMAR1GRIN2DGRIN3BGRIN1
Hydrochloric Acid SCHEMBL17846422 0.72 MAPT (0.44) EPHX2SIGMAR1GRIN2DGRIN3BGRIN1
SCHEMBL18747629 0.72 EPHX2 (0.50) EPHX2SIGMAR1GRIN2DGRIN3BGRIN1
SCHEMBL10036621 0.71 CA12 (0.37) ALDH1A1TDP1
SCHEMBL4892582 0.71 PPID (0.42) EPHX2SIGMAR1GRIN2DGRIN3BGRIN1
SCHEMBL17456133 0.71 MAPT (0.43) EPHX2SIGMAR1GRIN2DGRIN3BGRIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8828879-B2 Silicon-containing composition having sulfonamide group for forming resist underlayer film NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2014-09-09 US disclosed
EP-2479615-B1 SILICON-CONTAINING COMPOSITION HAVING SULFONAMIDE GROUP FOR FORMING RESIST UNDERLAYER FILM NISSAN CHEMICAL IND LTD (JP) 2014-04-23 EP disclosed
EP-2479615-A1 SILICON-CONTAINING COMPOSITION HAVING SULFONAMIDE GROUP FOR FORMING RESIST UNDERLAYER FILM Nissan Chemical Industries, Ltd. (JP) 2012-07-25 EP disclosed
US-20120178261-A1 SILICON-CONTAINING COMPOSITION HAVING SULFONAMIDE GROUP FOR FORMING RESIST UNDERLAYER FILM NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2012-07-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120178261-A1 SILICON-CONTAINING COMPOSITION HAVING SULFONAMIDE GROUP FOR FORMING RESIST UNDERLAYER FILM STS, SI, MUS81 EPHX2 2044/4885SIGMAR1 2871/4885GRIN2D 3248/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.