Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | IDH1 | O75874 | 2/20 | 0.38 |
| ▸ | F10 | P00742 | 6/20 | 0.37 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1096606 | 1.00 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1HPGDIDH1F10 | |
| SCHEMBL1096006 | 1.00 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1HPGDIDH1F10 | |
| SCHEMBL10313052 | 0.99 | SMN1; SMN2 (0.40) | SMN1; SMN2ALDH1A1HPGDIDH1F10 | |
| SCHEMBL1097203 | 0.99 | SMN1; SMN2 (0.40) | SMN1; SMN2ALDH1A1HPGDIDH1F10 | |
| SCHEMBL1096495 | 0.99 | SMN1; SMN2 (0.40) | SMN1; SMN2ALDH1A1HPGDIDH1F10 | |
| SCHEMBL1106541 | 0.82 | F10 (0.40) | SMN1; SMN2ALDH1A1HPGDF10NPC1 | |
| SCHEMBL1096165 | 0.82 | F10 (0.40) | SMN1; SMN2ALDH1A1HPGDF10NPC1 | |
| SCHEMBL1096412 | 0.81 | POLB (0.44) | SMN1; SMN2ALDH1A1HPGDF10LMNA | |
| SCHEMBL13886838 | 0.81 | IDH1 (0.34) | SMN1; SMN2ALDH1A1HPGDIDH1F10 | |
| SCHEMBL1095346 | 0.80 | POLB (0.45) | SMN1; SMN2ALDH1A1HPGDF10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8377974-B2 | Factor Xa inhibitors | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2013-02-19 | — | — | US | disclosed |
| US-20120178733-A1 | FACTOR XA INHIBITORS | MILLENNIUM PHARMACEUTICALS, INC. | 2012-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120178733-A1 | FACTOR XA INHIBITORS | TFPI, F12, F11 | SMN1; SMN2 4168/4885ALDH1A1 974/4885HPGD 316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.