Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 20/20 | 0.51 |
| ▸ | PGR | P06401 | 13/20 | 0.51 |
| ▸ | NR3C2 | P08235 | 14/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10313407 | 0.90 | NR3C1 (0.47) | NR3C1PGRNR3C2CYP3A4 | |
| SCHEMBL10313406 | 0.89 | NR3C1 (0.43) | NR3C1PGRNR3C2CYP3A4 | |
| SCHEMBL5781547 | 0.86 | NR3C1 (0.56) | NR3C1PGRNR3C2CYP3A4 | |
| SCHEMBL5798149 | 0.86 | NR3C1 (0.54) | NR3C1PGRNR3C2CYP3A4 | |
| SCHEMBL10313405 | 0.84 | NR3C1 (0.64) | NR3C1PGRNR3C2 | |
| SCHEMBL10313408 | 0.83 | NR3C1 (0.55) | NR3C1PGRNR3C2 | |
| SCHEMBL1633971 | 0.82 | NR3C1 (0.51) | NR3C1PGRNR3C2CYP3A4 | |
| SCHEMBL10313400 | 0.78 | NR3C1 (0.65) | NR3C1PGRNR3C2 | |
| SCHEMBL10313399 | 0.76 | NR3C1 (0.63) | NR3C1PGRNR3C2 | |
| SCHEMBL1633476 | 0.76 | NR3C1 (0.72) | NR3C1PGRNR3C2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8212040-B2 | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and thereof | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2012-07-03 | — | — | US | disclosed |
| US-7932392-B2 | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2011-04-26 | — | — | US | disclosed |
| US-7553966-B2 | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2009-06-30 | — | — | US | disclosed |