Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 5/20 | 0.34 |
| ▸ | CDC25B | P30305 | 5/20 | 0.34 |
| ▸ | PTPN2 | P17706 | 4/20 | 0.34 |
| ▸ | CDC25A | P30304 | 3/20 | 0.34 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 2/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | SELP | P16109 | 3/20 | 0.31 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
| ▸ | GJB2 | P29033 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10314508 | 0.85 | SELP (0.36) | PTPN1CDC25BPTPN2CDC25APTPN6 | |
| SCHEMBL14223578 | 0.85 | PTPN1 (0.37) | PTPN1CDC25BPTPN2CDC25APTPN6 | |
| SCHEMBL10314531 | 0.84 | SELP (0.39) | PTPN1CDC25BPTPN2CDC25APTPN6 | |
| SCHEMBL10314513 | 0.83 | PTPN1 (0.36) | PTPN1CDC25BPTPN2CDC25APTPN6 | |
| SCHEMBL10314514 | 0.82 | SELP (0.44) | PTPN1CDC25BPTPN2CDC25APTPN6 | |
| SCHEMBL10314533 | 0.82 | SELP (0.39) | PTPN1CDC25BPTPN2CDC25APTPN6 | |
| SCHEMBL16160561 | 0.81 | PTPN1 (0.38) | PTPN1CDC25BPTPN2CDC25APTPN6 | |
| SCHEMBL16160564 | 0.81 | PTPN1 (0.38) | PTPN1CDC25BPTPN2CDC25APTPN6 | |
| SCHEMBL10314510 | 0.77 | PTPN1 (0.44) | PTPN1CDC25BPTPN2CDC25APTPN6 | |
| SCHEMBL16151874 | 0.74 | GJB2 (0.36) | PTPN1CDC25BSELPTNFGJB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8211859-B2 | α-galactoceramide analogs, their methods of manufacture, intermediate compounds useful in these methods, and pharmaceutical compositions containing them | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2012-07-03 | — | — | US | disclosed |