Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TERT | O14746 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12836952 | 0.91 | KDM4E (0.36) | KDM4ECASP1CASP7HSD17B10L3MBTL1 | |
| SCHEMBL12763748 | 0.87 | KDM4E (0.36) | KDM4ECASP1CASP7HSD17B10L3MBTL1 | |
| SCHEMBL1410106 | 0.80 | TERT (0.43) | KDM4ECASP1CASP7HSD17B10L3MBTL1 | |
| SCHEMBL1517339 | 0.80 | TERT (0.43) | TERT | |
| SCHEMBL1409926 | 0.73 | TOP1 (0.44) | TERT | |
| SCHEMBL17018807 | 0.72 | KDM4E (0.38) | KDM4ECASP1CASP7HSD17B10L3MBTL1 | |
| SCHEMBL10314954 | 0.70 | TOP1 (0.43) | KDM4ECASP1CASP7HSD17B10L3MBTL1 | |
| SCHEMBL8001501 | 0.69 | TERT (0.37) | TERT | |
| SCHEMBL1410123 | 0.67 | STAT3 (0.50) | KDM4ECASP1CASP7HSD17B10L3MBTL1 | |
| SCHEMBL1410192 | 0.67 | TERT (0.46) | TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8217026-B2 | Substituted porphyrins | AEOLUS SCIENCES, INC. (US) | 2012-07-10 | — | — | US | disclosed |