SCHEMBL10315434

SCHEMBL10315434

Cc1ccc(-c2cc3nc(-c4ccc(N(c5ccccc5)c5ccc(-c6nc7ccccc7o6)cc5)cc4)c(-c4ccc(N(c5ccccc5)c5ccc(-c6nc7ccccc7o6)cc5)cc4)nc3cc2-c2ccc(C)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 10/20 0.48
RAB9A P51151 8/20 0.48
KDM4E B2RXH2 8/20 0.48
SMN1; SMN2 Q16637 7/20 0.48
HPGD P15428 7/20 0.48
CASP3 P42574 2/20 0.48
SENP8 Q96LD8 2/20 0.48
SENP7 Q9BQF6 2/20 0.48
SENP6 Q9GZR1 2/20 0.48
POLB P06746 1/20 0.48
ALDH1A1 P00352 7/20 0.47
HSD17B10 Q99714 4/20 0.47
TP53 P04637 3/20 0.47
PTPN2 P17706 2/20 0.46
PTPN1 P18031 2/20 0.46
PTPN5 P54829 2/20 0.46
TDP1 Q9NUW8 2/20 0.45
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
ATM Q13315 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10315196 0.99 NPC1 (0.50) NPC1RAB9AKDM4ESMN1; SMN2HPGD
SCHEMBL10315179 0.93 NPC1 (0.48) NPC1RAB9AKDM4ESMN1; SMN2HPGD
SCHEMBL10315424 0.93 NPC1 (0.48) NPC1RAB9AKDM4ESMN1; SMN2HPGD
SCHEMBL10315430 0.92 NPC1 (0.46) NPC1RAB9AKDM4ESMN1; SMN2HPGD
SCHEMBL10315415 0.92 NPC1 (0.47) NPC1RAB9AKDM4ESMN1; SMN2HPGD
SCHEMBL10315189 0.92 NPC1 (0.47) NPC1RAB9AKDM4ESMN1; SMN2HPGD
SCHEMBL10315203 0.92 TDP1 (0.54) NPC1RAB9AKDM4ESMN1; SMN2HPGD
SCHEMBL10315204 0.91 NPC1 (0.46) NPC1RAB9AKDM4ESMN1; SMN2HPGD
SCHEMBL10125945 0.90 NPC1 (0.57) NPC1RAB9AKDM4ESMN1; SMN2HPGD
SCHEMBL10315230 0.90 TDP1 (0.57) NPC1RAB9AKDM4ESMN1; SMN2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2067778-B1 Quinoxaline derivative, and light emitting element, light emitting device and electronic appliance using the same SEMICONDUCTOR ENERGY LAB (JP) 2016-08-17 EP disclosed
US-8216696-B2 Quinoxaline derivative, and light emitting element, light emitting device and electronic appliance using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-07-10 US disclosed
US-8216696-B2 Quinoxaline derivative, and light emitting element, light emitting device and electronic appliance using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-07-10 US disclosed
EP-2067778-A1 Quinoxaline derivative, and light emitting element, licht emitting device and electronic appliance using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2009-06-10 EP disclosed