Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR9 | P51686 | 5/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.38 |
| ▸ | SQSTM1 | Q13501 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4246509 | 0.99 | CCR9 (0.44) | CCR9FFAR4TP53SLC40A1PKM | |
| SCHEMBL1033616 | 0.89 | PKM (0.39) | TP53PKMSQSTM1KEAP1NFE2L2 | |
| SCHEMBL1031476 | 0.89 | FFAR4 (0.40) | CCR9FFAR4TP53SLC40A1HDAC3 | |
| Hydrochloric Acid SCHEMBL4240512 | 0.89 | PKM (0.39) | TP53PKMSQSTM1KEAP1NFE2L2 | |
| Hydrochloric Acid SCHEMBL4240168 | 0.88 | FFAR4 (0.40) | CCR9FFAR4TP53SLC40A1HDAC3 | |
| SCHEMBL1033689 | 0.87 | PKM (0.43) | TP53PKMSQSTM1KEAP1NFE2L2 | |
| SCHEMBL1029498 | 0.86 | KIT (0.41) | TP53PKMSQSTM1KEAP1NFE2L2 | |
| Hydrochloric Acid SCHEMBL4251154 | 0.86 | PKM (0.42) | TP53PKMSQSTM1KEAP1NFE2L2 | |
| Hydrochloric Acid SCHEMBL4243947 | 0.85 | KIT (0.41) | TP53PKMSQSTM1KEAP1NFE2L2 | |
| SCHEMBL1033640 | 0.85 | PKM (0.39) | TP53PKMSQSTM1KEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2013179-B1 | ARYLOXYETHYLAMINE COMPOUNDS SUITABLE FOR TREATING DISORDERS THAT RESPOND TO MODULATION OF THE DOPAMINE D3 RECEPTOR | ABBOTT GMBH & CO KG (DE) | 2011-01-19 | — | — | EP | disclosed |