⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15653296 | 0.90 | — | — | |
| SCHEMBL31411083 | 0.86 | — | — | |
| SCHEMBL15524497 | 0.83 | — | — | |
| SCHEMBL4570492 | 0.83 | — | — | |
| SCHEMBL15524499 | 0.83 | — | — | |
| SCHEMBL19385898 | 0.83 | LMNA (0.35) | — | |
| SCHEMBL5678713 | 0.82 | — | — | |
| SCHEMBL18187478 | 0.82 | — | — | |
| SCHEMBL29235512 | 0.82 | — | — | |
| SCHEMBL12865774 | 0.82 | LMNA (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8791144-B2 | Substituted N-phenyl-1-(4-Pyridinyl)-1H-pyrazol-3-amines | JANSSEN PHARMACEUTICA NV (BE) | 2014-07-29 | — | — | US | disclosed |
| US-20120172354-A1 | Substituted N-Phenyl-1-(4-Pyridinyl)-1H-Pyrazol-3-Amines | JANSSEN PHARMACEUTICA NV (BE) | 2012-07-05 | — | — | US | disclosed |