SCHEMBL10316588

SCHEMBL10316588

CN(Cc1ccccc1)c1ccc(CN(Cc2cccc(C(=O)N(CC(=O)O)C(=O)OC(C)(C)C)n2)S(=O)(=O)c2cccnc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTGER2 P43116 20/20 0.56
PTGER4 P35408 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL533650 0.91 PTGER2 (0.61) PTGER2
SCHEMBL3459287 0.89 PTGER2 (0.55) PTGER2
SCHEMBL10316585 0.87 PTGER2 (0.64) PTGER2PTGER4
SCHEMBL12982974 0.83 PTGER2 (0.62) PTGER2
SCHEMBL533452 0.82 PTGER2 (0.64) PTGER2
SCHEMBL533554 0.82 PTGER2 (0.64) PTGER2
SCHEMBL10317221 0.79 PTGER2 (0.61) PTGER2
SCHEMBL10316922 0.79 PTGER2 (0.79) PTGER2PTGER4
SCHEMBL12982535 0.78 PTGER2 (0.50) PTGER2
SCHEMBL12983636 0.78 PTGER2 (0.54) PTGER2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2476668-B1 ANILINE COMPOUNDS UBE INDUSTRIES (JP) 2013-11-06 EP disclosed
US-20120184747-A1 ANILINE COMPOUND UBE INDUSTRIES, LTD. (JP) 2012-07-19 US disclosed
EP-2476668-A1 ANILINE COMPOUNDS Ube Industries, Ltd. (JP) 2012-07-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120184747-A1 ANILINE COMPOUND PTGER2, ADRB2, PTGER1 PTGER2 1/4885PTGER4 5/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.