Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | KDM5C | P41229 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3015657 | 0.81 | MAPT (0.39) | LMNATSHRALDH1A1GAAKMT2A | |
| SCHEMBL3019716 | 0.80 | MAPT (0.39) | LMNATSHRALDH1A1GAAKMT2A | |
| SCHEMBL3477764 | 0.79 | ALDH1A1 (0.40) | TSHRALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL3022329 | 0.77 | CHRM3 (0.37) | KMT2AKDM4EMEN1TP53MAPT | |
| SCHEMBL3016482 | 0.75 | ALDH1A1 (0.36) | LMNATSHRALDH1A1KMT2AKDM4E | |
| SCHEMBL3021494 | 0.75 | ALDH1A1 (0.36) | LMNATSHRALDH1A1KMT2AKDM4E | |
| SCHEMBL19529557 | 0.72 | ALDH1A1 (0.39) | LMNATSHRALDH1A1KMT2AKDM4E | |
| SCHEMBL2822250 | 0.71 | CYP1A2 (0.55) | LMNAALDH1A1GAAKDM4EMAPT | |
| SCHEMBL3021173 | 0.71 | ALDH1A1 (0.38) | TSHRALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL3019178 | 0.70 | ALDH1A1 (0.31) | LMNATSHRALDH1A1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8221719-B2 | Luminescent lanthanide (III) chelates, chelating agents and conjugates derived thereof | WALLAC OY (FI) | 2012-07-17 | — | — | US | disclosed |