⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1028266 | 0.72 | — | — | |
| SCHEMBL11583703 | 0.67 | — | — | |
| SCHEMBL5518651 | 0.67 | — | — | |
| Fluoroacetate SCHEMBL78188 | 0.67 | — | — | |
| SCHEMBL92092 | 0.67 | — | — | |
| SCHEMBL6706926 | 0.67 | — | — | |
| SCHEMBL88444 | 0.67 | — | — | |
| SCHEMBL5106 | 0.67 | — | — | |
| Fluoroacetate SCHEMBL13651728 | 0.67 | — | — | |
| Fluoroacetate SCHEMBL5908770 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 161 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024091882-A1 | SMALL MOLECULE DIRECT INHIBITORS OF KEAP1-NRF2 PROTEIN-PROTEIN INTERACTION | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2024-05-02 | — | — | WO | claimed |
| US-20090042957-A1 | Substituted Oxyarenes | BAYER CROPSCIENCE AG (DE) | 2009-02-12 | — | — | US | claimed |
| JP-2008525370-A | — | — | 2008-07-17 | — | — | JP | claimed |
| EP-1830843-A2 | INDOLIDONE DERIVATIVES FOR THE TREATMENT OR PREVENTION OF FIBROTIC DISEASES | Boehringer Ingelheim International GmbH (DE) | 2007-09-12 | — | — | EP | claimed |
| EP-1831145-A1 | SUBSTITUTED OXYARENES | Bayer CropScience Aktiengesellschaft (DE) | 2007-09-12 | — | — | EP | claimed |
| WO-2006069685-A1 | SUBSTITUTED OXYARENES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2006-07-06 | — | — | WO | claimed |
| WO-2006067165-A2 | INDOLIDONE DERIVATIVES FOR THE TREATMENT OR PREVENTION OF FIBROTIC DISEASES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-06-29 | — | — | WO | claimed |
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | claimed |
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-06-10 | — | — | US | claimed |
| WO-2004018428-A1 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | claimed |
| EP-0639195-B1 | 2-ACYLOXYCEPHEM DERIVATIVES AS ELASTASE INHIBITORS | PHARMACIA & UPJOHN SPA (IT) | 1999-05-26 | — | — | EP | claimed |
| US-5587373-A | ELASTASE INHIBITORS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1996-12-24 | — | — | US | claimed |
| EP-0337704-B1 | Beta-lactam derivatives | PHARMACIA SPA (IT) | 1995-06-14 | — | — | EP | claimed |
| EP-0639195-A1 | 2-ACYLOXYCEPHEM DERIVATIVES AS ELASTASE INHIBITORS | PHARMACIA & UPJOHN S.p.A. (IT) | 1995-02-22 | — | — | EP | claimed |
| WO-1994020504-A1 | 2-ACYLOXYCEPHEM DERIVATIVES AS ELASTASE INHIBITORS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1994-09-15 | — | — | WO | claimed |
| EP-0280240-B1 | Cephalosporin derivatives, process for their preparation and antibacterial agents | BANYU PHARMA CO LTD (JP) | 1994-09-14 | — | — | EP | claimed |
| EP-0505413-A1 | BETA-LACTAM DERIVATIVES. | ERBA FARMITALIA (IT) | 1992-09-30 | — | — | EP | claimed |
| US-5077286-A | Human leukocyte elastase inhibitor | FARMITALIA CARLO ERBA S.R.L. (IT) | 1991-12-31 | — | — | US | claimed |
| WO-1991009036-A1 | BETA-LACTAM DERIVATIVES | FARMITALIA CARLO ERBA S.R.L. (IT) | 1991-06-27 | — | — | WO | claimed |
| EP-0337704-A2 | Beta-lactam derivatives | PHARMACIA S.p.A. (IT) | 1989-10-18 | — | — | EP | claimed |