SCHEMBL88444

SCHEMBL88444

O=C(CF)CF

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9971728 0.82
SCHEMBL21816673 0.79
SCHEMBL27962006 0.79
SCHEMBL7064243 0.76
SCHEMBL12443749 0.76
SCHEMBL25361121 0.76
SCHEMBL9847499 0.76
SCHEMBL12111379 0.76
SCHEMBL1512109 0.76
SCHEMBL1939612 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1910 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250353912-A1 COMPOSITIONS AND METHODS COMPRISING ANTIBODIES THAT BIND TO COVALENT PEPTIDE CONJUGATES UNIV NEW YORK (US) 2025-11-20 US claimed
EP-3946437-B1 EX VIVO METHODS FOR PRODUCING A T CELL THERAPEUTIC AND RELATED COMPOSITIONS AND METHODS H LEE MOFFITT CANCER CT & RES (US) 2025-11-19 EP claimed
EP-4543931-A2 COMPOSITIONS AND METHODS COMPRISING ANTIBODIES THAT BIND TO COVALENT PEPTIDE CONJUGATES New York University (US) 2025-04-30 EP claimed
CN-119866347-A Compositions and methods comprising antibodies conjugated to covalent peptide conjugates 纽约大学 2025-04-22 CN claimed
CN-112368295-B Ionic self-assembled peptides 立美基股份有限公司 2025-03-21 CN claimed
CN-119585265-A Novel heterocyclic compound and pharmaceutical composition for inhibiting autotaxin comprising same 株式会社次代生物科学 2025-03-07 CN claimed
CN-111849955-B Immobilization and isolation of extracellular nucleic acids 预先分析股份有限公司 2025-01-10 CN claimed
WO-2023250391-A9 COMPOSITIONS AND METHODS COMPRISING ANTIBODIES THAT BIND TO COVALENT PEPTIDE CONJUGATES NEW YORK UNIVERSITY (US) 2024-04-25 WO claimed
WO-2023250391-A2 COMPOSITIONS AND METHODS COMPRISING ANTIBODIES THAT BIND TO COVALENT PEPTIDE CONJUGATES NEW YORK UNIVERSITY (US) 2023-12-28 WO claimed
US-11834698-B2 Process for determining enzyme activity in a cell by activity-based reporter gene technology (ABRGT) INDIAN INSTITUTE OF SCIENCE EDUCATION AND RESEARCH (IN) 2023-12-05 US claimed
US-5458806-A Fluoromethyl ketones and liquid-crystalline media MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1995-10-17 US claimed
US-5284829-A Containing phenylalanine, alanine, proline, leucine and having blocking group on amine end and protease inhibiting group on carboxylic acid end of molecule THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1994-02-08 US claimed
US-5210272-A Using a magnesium fluoromalonate to fluoromethylate a carboxylic acid PROTOTEK, INC. (US) 1993-05-11 US claimed
WO-1991015577-A1 INTERLEUKIN 1'beta' PROTEASE BLACK, ROY, A. 1991-10-17 WO claimed
EP-0442754-A2 Reagents and methods for stereospecific fluoromethylation PROTOTEK, INC., (US) 1991-08-21 EP claimed
EP-0364561-A4 FACTOR VII/VIIA ACTIVE SITE INHIBITORS 1991-06-19 EP claimed
US-5023236-A Tripeptides having an arginine at the C-terminus and a hydroxy-containing amino acid in the second position; anticoagulants; antiinflammatory agents; reversible CORVAS, INC. (US) 1991-06-11 US claimed
EP-0364561-A1 FACTOR VII/VIIa ACTIVE SITE INHIBITORS CORVAS, INC. (US) 1990-04-25 EP claimed
WO-1990002175-A1 A METHOD OF PRODUCING POLYPEPTIDES BY CULTURING EUKARYOTIC CELLS IN THE PRESENCE OF PROTEASE INHIBITORS NOVO NORDISK A/S (DK) 1990-03-08 WO claimed
WO-1989009612-A1 FACTOR VII/VIIa ACTIVE SITE INHIBITORS CORVAS, INC. (US) 1989-10-19 WO claimed