SCHEMBL1031807

SCHEMBL1031807

Cc1cc(C(=O)CCc2sc3ccccc3c2C)ccc1OCC(=O)O

nearest known ligand 0.45

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.45
PTPN1 P18031 8/20 0.43
PPARD Q03181 6/20 0.42
PPARG P37231 2/20 0.41
PPARA Q07869 1/20 0.41
PTPN2 P17706 1/20 0.41
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.39
KDM4E B2RXH2 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1034038 0.89 ABCB1 (0.46) CYP1A2KMT2AL3MBTL1KDM4E
SCHEMBL1035193 0.84 PPARD (0.47) PPARDPPARGPPARA
SCHEMBL1032851 0.84 PPARD (0.47) PPARDPPARGPPARA
SCHEMBL1035257 0.84 PTPN7 (0.44) CYP1A2PPARDPPARGPPARAKDM4E
SCHEMBL1035525 0.81 CYP1A2 (0.45) CYP1A2MEN1KMT2AL3MBTL1KDM4E
SCHEMBL1034852 0.79 FBP1 (0.41) CYP1A2PPARGPPARAMEN1KMT2A
SCHEMBL10315719 0.75 PRNP (0.47) CYP1A2PTPN1
SCHEMBL1034041 0.75 ESR1 (0.43) PPARDPPARGPPARA
SCHEMBL1034264 0.75 ESR1 (0.43) PPARDPPARGPPARA
SCHEMBL1031604 0.74 PPARD (0.45) PPARDPPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2277874-B1 ACTIVATOR FOR PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR NIPPON CHEMIPHAR CO (JP) 2018-06-27 EP claimed
US-20110098480-A1 ACTIVATING AGENT FOR PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR NIPPON CHEMIPHAR CO. LTD. (JP) 2011-04-28 US claimed
EP-2277874-A1 ACTIVATOR FOR PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR Nippon Chemiphar Co., Ltd. (JP) 2011-01-26 EP claimed
US-20190255022-A1 WOUND-HEALING AGENT NIPPON CHEMIPHAR CO., LTD. (JP) 2019-08-22 US disclosed
EP-3456327-A1 WOUND-HEALING AGENT Nippon Chemiphar Co., Ltd. (JP) 2019-03-20 EP disclosed
EP-3424917-A1 ACTIVATOR FOR PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR Nippon Chemiphar Co., Ltd. (JP) 2019-01-09 EP disclosed
EP-2277874-B1 ACTIVATOR FOR PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR NIPPON CHEMIPHAR CO (JP) 2018-06-27 EP disclosed
US-8648208-B2 Activating agent for peroxisome proliferator activated receptor NIPPON CHEMIPHAR CO. LTD. (JP) 2014-02-11 US disclosed
US-20110098480-A1 ACTIVATING AGENT FOR PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR NIPPON CHEMIPHAR CO. LTD. (JP) 2011-04-28 US disclosed
EP-2277874-A1 ACTIVATOR FOR PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR Nippon Chemiphar Co., Ltd. (JP) 2011-01-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190255022-A1 WOUND-HEALING AGENT PPARG, PPARA, PPARD CYP1A2 1583/4885PTPN1 2672/4885PPARD 3/4885
US-20110098480-A1 ACTIVATING AGENT FOR PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR PPARA, PPARG, PPARD CYP1A2 792/4885PTPN1 898/4885PPARD 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.