Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 20/20 | 0.82 |
| ▸ | DYRK1B | Q9Y463 | 16/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10319248 | 1.00 | DYRK1A (0.82) | DYRK1ADYRK1B | |
| SCHEMBL10320005 | 1.00 | DYRK1A (0.82) | DYRK1ADYRK1B | |
| SCHEMBL10320615 | 0.94 | DYRK1A (0.76) | DYRK1ADYRK1B | |
| SCHEMBL11951032 | 0.94 | DYRK1A (0.73) | DYRK1ADYRK1B | |
| SCHEMBL10379957 | 0.92 | DYRK1A (0.80) | DYRK1ADYRK1B | |
| SCHEMBL10379493 | 0.92 | DYRK1A (0.80) | DYRK1ADYRK1B | |
| SCHEMBL10379231 | 0.92 | DYRK1A (0.80) | DYRK1ADYRK1B | |
| SCHEMBL10321521 | 0.88 | DYRK1A (0.66) | DYRK1ADYRK1B | |
| SCHEMBL10380135 | 0.87 | DYRK1A (0.88) | DYRK1ADYRK1B | |
| SCHEMBL10379227 | 0.87 | DYRK1A (0.88) | DYRK1ADYRK1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120184548-A1 | CARBOXYLIC ACID ARYL AMIDES | DOMINIQUE ROMYR (US) | 2012-07-19 | — | — | US | claimed |
| US-20120184548-A1 | CARBOXYLIC ACID ARYL AMIDES | DOMINIQUE ROMYR (US) | 2012-07-19 | — | — | US | disclosed |
| US-20120184548-A1 | CARBOXYLIC ACID ARYL AMIDES | DOMINIQUE ROMYR (US) | 2012-07-19 | — | — | US | disclosed |
| US-20120184548-A1 | CARBOXYLIC ACID ARYL AMIDES | DOMINIQUE ROMYR (US) | 2012-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120184548-A1 | CARBOXYLIC ACID ARYL AMIDES | GOT1, PPARG, PPARA | DYRK1A 2480/4885DYRK1B 3023/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.