⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21350260 | 1.00 | — | — | |
| SCHEMBL3394564 | 1.00 | — | — | |
| SCHEMBL14601490 | 0.78 | — | — | |
| SCHEMBL13577729 | 0.78 | — | — | |
| SCHEMBL7816966 | 0.78 | — | — | |
| SCHEMBL52211 | 0.76 | — | — | |
| SCHEMBL574767 | 0.76 | — | — | |
| SCHEMBL3277293 | 0.76 | — | — | |
| SCHEMBL31536825 | 0.75 | LMNA (0.39) | — | |
| SCHEMBL14601499 | 0.73 | CYP2D6 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8546083-B2 | Molecular accessibility assay | UNIVERSITY OF VERMONT (US) | 2013-10-01 | — | — | US | claimed |
| US-20100047791-A1 | MOLECULAR ACCESSIBILITY ASSAY | NATIONAL INSTITUTES OF HEALTH | 2010-02-25 | — | — | US | claimed |
| WO-2008091541-A1 | MOLECULAR ACCESSIBILITY ASSAY | UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE (US) | 2008-07-31 | — | — | WO | claimed |
| EP-4720331-A1 | FALSE POSITIVE REDUCTION BY TRANSLESION POLYMERASE REPAIR | Illumina, Inc. (US) | 2026-04-08 | — | — | EP | disclosed |
| EP-4705313-A2 | 4'-SUBSTITUTED NUCLEOSIDES AND NUCLEOTIDES AS ANTIVIRAL AGENTS | The Scripps Research Institute (US) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024249466-A1 | FALSE POSITIVE REDUCTION BY TRANSLESION POLYMERASE REPAIR | ILLUMINA, INC. (US) | 2024-12-05 | — | — | WO | disclosed |
| WO-2024227159-A2 | 4'-SUBSTITUTED NUCLEOSIDES AND NUCLEOTIDES AS ANTIVIRAL AGENTS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2024-10-31 | — | — | WO | disclosed |
| CN-104755469-B | The manufacture method of difluoro ester compounds | 旭硝子株式会社 | 2018-04-10 | — | — | CN | disclosed |
| US-20170334941-A1 | 2',2'-DIHALO NUCLEOSIDE ANALOGS FOR TREATMENT OF THE FLAVIVIRIDAE FAMILY OF VIRUSES AND CANCER | EMORY UNIVERSITY | 2017-11-23 | — | — | US | disclosed |
| US-9790252-B2 | 2-fluorinated riboses and arabinoses and methods of use and synthesis | CORNELL UNIVERSITY (US) | 2017-10-17 | — | — | US | disclosed |
| EP-3212658-A1 | 2',2'-DIHALO NUCLEOSIDE ANALOGS FOR TREATMENT OF THE FLAVIVIRIDAE FAMILY OF VIRUSES AND CANCER | Cocrystal Pharma, Inc. (US) | 2017-09-06 | — | — | EP | disclosed |
| US-20050112555-A1 | Cytidine deaminase activators, deoxycytidine deaminase activators, Vif antagonists, and methods of screening for molecules thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-05-26 | — | — | US | disclosed |
| WO-2005023985-A2 | CYTIDINE DEAMINASE ACTIVATORS, DEOXYCYTIDINE DEAMINASE ACTIVATORS, VIF ANTAGONISTS, AND METHODS OF SCREENING FOR MOLECULES THEREOF | UNIVERSITY OF ROCHESTER (US) | 2005-03-17 | — | — | WO | disclosed |
| US-20050054042-A1 | Novel gluconate dehydratase | MITSUI CHEMICALS, INC. (JP) | 2005-03-10 | — | — | US | disclosed |
| EP-1496113-A1 | Gluconate dehydratase | MITSUI CHEMICALS, INC. (JP) | 2005-01-12 | — | — | EP | disclosed |
| WO-2004113358-A1 | PRODUCTION OF 2'-DEOXYNUCLEOSIDES AND 2'-DEOXYNUCLEOSIDE PRECURSORS FROM 2-DEHYDRO-3-DEOXY-D-GLUCONATE | EVOLOGIC S.A. (FR) | 2004-12-29 | — | — | WO | disclosed |
| WO-2001072698-A1 | OPTICALLY ACTIVE CYANOBUTANTRIOL DERIVATIVES AND PROCESS FOR PREPARING SAME | KUKJE PHARMA. IND. CO., LTD. (KR) | 2001-10-04 | — | — | WO | disclosed |
| US-5721350-A | Deuterated nucleosides | CHATTOPADHYAYA JYOTI (SE) | 1998-02-24 | — | — | US | disclosed |
| EP-0648220-A1 | DEUTERATED NUCLEOSIDES | CHATTOPADHYAYA, Jyoti (SE) | 1995-04-19 | — | — | EP | disclosed |
| WO-1993025566-A1 | DEUTERATED NUCLEOSIDES | CHATTOPADHYAYA JYOTI (SE) | 1993-12-23 | — | — | WO | disclosed |