Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 known ✓ | P35372 | 4/20 | 0.46 |
| ▸ | CCR5 | P51681 | 5/20 | 0.51 |
| ▸ | HTR2A | P28223 | 9/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL10322317 | 1.00 | CCR5 (0.51) | CCR5HTR2AOPRM1TMEM97 | |
| Oxalic Acid SCHEMBL10322318 | 1.00 | CCR5 (0.51) | CCR5HTR2AOPRM1TMEM97 | |
| SCHEMBL340996 | 0.98 | CCR5 (0.51) | CCR5HTR2AOPRM1TMEM97 | |
| SCHEMBL340995 | 0.98 | CCR5 (0.51) | CCR5HTR2AOPRM1TMEM97 | |
| SCHEMBL340997 | 0.98 | CCR5 (0.51) | CCR5HTR2AOPRM1TMEM97 | |
| Oxalic Acid SCHEMBL5927650 | 0.94 | CCR5 (0.51) | CCR5HTR2AOPRM1TMEM97 | |
| Oxalic Acid SCHEMBL5927636 | 0.94 | CCR5 (0.51) | CCR5HTR2AOPRM1TMEM97 | |
| Oxalic Acid SCHEMBL5927639 | 0.94 | CCR5 (0.51) | CCR5HTR2AOPRM1TMEM97 | |
| SCHEMBL340156 | 0.92 | CCR5 (0.51) | CCR5HTR2AOPRM1TMEM97 | |
| SCHEMBL340155 | 0.92 | CCR5 (0.51) | CCR5HTR2AOPRM1TMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120183600-A1 | NOVEL COMPOSITION FOR TREATING METABOLIC SYNDROME AND OTHER CONDITIONS | CHEN CHIEN-HUNG (US) | 2012-07-19 | — | — | US | claimed |
| US-20140350064-A1 | PHARMACEUTICAL COMPOSITION COMPRISING AN AMPK ACTIVATOR AND A SEROTONERGIC AGENT AND METHODS OF USE THEREOF | ALS MOUNTAIN LLC | 2014-11-27 | — | — | US | disclosed |
| US-20120183600-A1 | NOVEL COMPOSITION FOR TREATING METABOLIC SYNDROME AND OTHER CONDITIONS | CHEN CHIEN-HUNG (US) | 2012-07-19 | — | — | US | disclosed |