SCHEMBL10323317

SCHEMBL10323317

CC(C)(C)OC(=O)N(c1cccc(C(Cc2ccc(N(c3ccccc3)c3ccccc3)cc2)NS(=O)(=O)c2cccnc2)n1)C(C(=O)O)C(C)(C)C

nearest known ligand 0.34

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SLC1A3 P43003 1/20 0.34
SLC1A2 P43004 1/20 0.34
SLC1A1 P43005 1/20 0.34
P2RX7 Q99572 2/20 0.33
PTGER2 P43116 5/20 0.33
PTPRB P23467 1/20 0.33
F2 P00734 2/20 0.33
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
CYP3A4 P08684 3/20 0.32
ADAMTS4 O75173 1/20 0.32
ADAM17 P78536 1/20 0.32
USP30 Q70CQ3 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL534320 0.93 PTGER2 (0.38) SLC1A3SLC1A2SLC1A1P2RX7PTGER2
SCHEMBL533795 0.91 SLC1A3 (0.35) SLC1A3SLC1A2SLC1A1P2RX7PTGER2
SCHEMBL10322183 0.91 PTPRB (0.35) SLC1A3SLC1A2SLC1A1P2RX7PTGER2
SCHEMBL533698 0.90 PTGER2 (0.42) SLC1A3SLC1A2SLC1A1PTGER2PTPRB
SCHEMBL533714 0.89 PTGER2 (0.40) SLC1A3SLC1A2SLC1A1PTGER2PTPRB
SCHEMBL534170 0.89 PTGER2 (0.40) SLC1A3SLC1A2SLC1A1PTGER2ADAMTS4
SCHEMBL534195 0.88 PTGER2 (0.41) SLC1A3SLC1A2SLC1A1P2RX7PTGER2
SCHEMBL13571751 0.88 PTGER2 (0.42) SLC1A3SLC1A2SLC1A1P2RX7PTGER2
SCHEMBL17472618 0.87 PTGER2 (0.47) PTGER2F2ADAMTS4
SCHEMBL15361809 0.87 PTGER2 (0.37) SLC1A3SLC1A2SLC1A1P2RX7PTGER2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120184747-A1 ANILINE COMPOUND UBE INDUSTRIES, LTD. (JP) 2012-07-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120184747-A1 ANILINE COMPOUND PTGER2, ADRB2, PTGER1 SLC1A3 1474/4885SLC1A2 615/4885SLC1A1 968/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.