Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 14/20 | 0.64 |
| ▸ | DYRK1B | Q9Y463 | 11/20 | 0.64 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10321365 | 0.89 | DYRK1A (0.80) | DYRK1ADYRK1BMAPK14L3MBTL1TSHR | |
| SCHEMBL10318061 | 0.86 | DYRK1A (0.85) | DYRK1ADYRK1BMAPK14 | |
| SCHEMBL10317577 | 0.86 | DYRK1A (0.85) | DYRK1ADYRK1BMAPK14 | |
| SCHEMBL10379514 | 0.82 | DYRK1A (0.90) | DYRK1ADYRK1B | |
| SCHEMBL10318005 | 0.81 | DYRK1A (0.73) | DYRK1ADYRK1BCNR2 | |
| SCHEMBL10379493 | 0.81 | DYRK1A (0.80) | DYRK1ADYRK1B | |
| SCHEMBL10379957 | 0.81 | DYRK1A (0.80) | DYRK1ADYRK1B | |
| SCHEMBL10379231 | 0.81 | DYRK1A (0.80) | DYRK1ADYRK1B | |
| SCHEMBL10318281 | 0.79 | DYRK1A (1.00) | DYRK1ADYRK1BMAPK14 | |
| SCHEMBL10318259 | 0.79 | DYRK1A (0.74) | DYRK1ADYRK1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120184548-A1 | CARBOXYLIC ACID ARYL AMIDES | DOMINIQUE ROMYR (US) | 2012-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120184548-A1 | CARBOXYLIC ACID ARYL AMIDES | GOT1, PPARG, PPARA | DYRK1A 2480/4885DYRK1B 3023/4885MAPK14 1729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.