Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | LSS | P48449 | 2/20 | 0.42 |
| ▸ | KDM5A | P29375 | 3/20 | 0.38 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.38 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 3/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL644854 | 0.98 | SIGMAR1 (0.62) | SIGMAR1CYP1A2LSSKDM5APHF8 | |
| SCHEMBL8855135 | 0.96 | SIGMAR1 (0.66) | SIGMAR1CYP1A2LSSKDM5APHF8 | |
| SCHEMBL8711529 | 0.96 | SIGMAR1 (0.66) | SIGMAR1CYP1A2LSSKDM5APHF8 | |
| Hydrochloric Acid SCHEMBL9520541 | 0.94 | SIGMAR1 (0.63) | SIGMAR1CYP1A2LSSKDM5APHF8 | |
| Water SCHEMBL9246810 | 0.94 | SIGMAR1 (0.63) | SIGMAR1CYP1A2LSSKDM5APHF8 | |
| Water SCHEMBL9248198 | 0.94 | SIGMAR1 (0.63) | SIGMAR1CYP1A2LSSKDM5APHF8 | |
| Water SCHEMBL9249880 | 0.94 | SIGMAR1 (0.63) | SIGMAR1CYP1A2LSSKDM5APHF8 | |
| Hydrochloric Acid SCHEMBL9516763 | 0.94 | SIGMAR1 (0.63) | SIGMAR1CYP1A2LSSKDM5APHF8 | |
| Hydrochloric Acid SCHEMBL9518737 | 0.94 | SIGMAR1 (0.63) | SIGMAR1CYP1A2LSSKDM5APHF8 | |
| Water SCHEMBL9249103 | 0.94 | SIGMAR1 (0.63) | SIGMAR1CYP1A2LSSKDM5APHF8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2663400-A1 | PROCESS OF MAKING MODIFIED METALLOCENE CATALYST, CATALYST PRODUCED AND USE THEREOF | W. R. Grace & Co.-Conn (US) | 2013-11-20 | — | — | EP | disclosed |
| WO-2012097146-A1 | PROCESS OF MAKING MODIFIED METALLOCENE CATALYST, CATALYST PRODUCED AND USE THEREOF | W. R. GRACE & CO.-CONN. (US) | 2012-07-19 | — | — | WO | disclosed |