Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE2 | P0DPD6 | 2/20 | 1.00 |
| ▸ | NPC1 | O15118 | 10/20 | 0.66 |
| ▸ | RAB9A | P51151 | 9/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.66 |
| ▸ | PKM | P14618 | 2/20 | 0.66 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.66 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.66 |
| ▸ | RELA | Q04206 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.61 |
| ▸ | MAPT | P10636 | 7/20 | 0.61 |
| ▸ | LMNA | P02545 | 6/20 | 0.61 |
| ▸ | MEN1 | O00255 | 6/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.56 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.54 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.54 |
| ▸ | NR0B1 | P51843 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15549880 | 1.00 | ECE2 (1.00) | ECE2NPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL30163114 | 1.00 | ECE2 (1.00) | ECE2NPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL10325191 | 1.00 | ECE2 (1.00) | ECE2NPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL31060773 | 1.00 | ECE2 (1.00) | ECE2NPC1RAB9ASMN1; SMN2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL15550704 | 0.98 | ECE2 (0.97) | ECE2NPC1RAB9ASMN1; SMN2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL15550705 | 0.98 | ECE2 (0.97) | ECE2NPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL4881278 | 0.91 | ECE2 (0.83) | ECE2NPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL9867682 | 0.89 | ECE2 (0.79) | ECE2NPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL9867671 | 0.89 | ECE2 (0.79) | ECE2NPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL15548939 | 0.84 | ECE2 (0.72) | ECE2NPC1RAB9ASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3161061-B1 | METHOD OF FORMING A PATTERNED THIN FILM COMPONENT AND ORGANIC THIN FILM TRANSISTOR | FLEXTERRA INC (US) | 2020-11-18 | — | — | EP | disclosed |
| CN-106663736-B | Photopatternable composition, patterned high dielectric thin film dielectric and related devices | 飞利斯有限公司 | 2020-01-17 | — | — | CN | disclosed |
| US-10409159-B2 | Photopatternable compositions, patterned high k thin film dielectrics and related devices | FLEXTERRA, INC. (US) | 2019-09-10 | — | — | US | disclosed |
| EP-3147280-B1 | ANTI-ANGIOGENIC COMPOUND | UNIV COLLEGE DUBLIN NAT UNIV IRELAND DUBLIN (IE) | 2018-03-07 | — | — | EP | disclosed |
| US-9815788-B2 | Anti-angiogenic compounds | THE PROVOST, FELLOWS, FOUNDATION SCHOLARS, AND THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN (IE) | 2017-11-14 | — | — | US | disclosed |
| US-9815788-B2 | Anti-angiogenic compounds | THE PROVOST, FELLOWS, FOUNDATION SCHOLARS, AND THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN (IE) | 2017-11-14 | — | — | US | disclosed |
| US-9815788-B2 | Anti-angiogenic compounds | THE PROVOST, FELLOWS, FOUNDATION SCHOLARS, AND THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN (IE) | 2017-11-14 | — | — | US | disclosed |
| US-20170192354-A1 | PHOTOPATTERNABLE COMPOSITIONS, PATTERNED HIGH K THIN FILM DIELECTRICS AND RELATED DEVICES | USINVEST LLC | 2017-07-06 | — | — | US | disclosed |
| CN-106663736-A | Photopatternable compositions, patterned high k thin film dielectrics and related devices | 飞利斯有限公司 | 2017-05-10 | — | — | CN | disclosed |
| EP-3161061-A1 | PHOTOPATTERNABLE COMPOSITIONS, PATTERNED HIGH K THIN FILM DIELECTRICS AND RELATED DEVICES | Flexterra, Inc. (US) | 2017-05-03 | — | — | EP | disclosed |
| US-20150218100-A1 | ANTI-ANGIOGENIC COMPOUNDS | UNIVERSITY COLLEGE DUBLIN NATIONAL UNIVERSITY OF IRELAND, DUBLIN (IE) | 2015-08-06 | — | — | US | disclosed |
| EP-2877454-A1 | ANTI-ANGIOGENIC COMPOUNDS | University College Dublin National University Of Ireland, Dublin (IE) | 2015-06-03 | — | — | EP | disclosed |
| US-8916586-B2 | Anti-angiogenic compound | University College Dublin—National University of Ireland, Dublin (IE) | 2014-12-23 | — | — | US | disclosed |
| US-8916586-B2 | Anti-angiogenic compound | University College Dublin—National University of Ireland, Dublin (IE) | 2014-12-23 | — | — | US | disclosed |
| WO-2014012889-A1 | ANTI-ANGIOGENIC COMPOUNDS | UNIVERSITY COLLEGE DUBLIN - NATIONAL UNIVERSITY OF IRELAND, DUBLIN (IE) | 2014-01-23 | — | — | WO | disclosed |
| EP-2663307-A1 | ANTI-ANGIOGENIC COMPOUND | University College Dublin National University Of Ireland, Dublin (IE) | 2013-11-20 | — | — | EP | disclosed |
| US-20130289066-A1 | ANTI-ANGIOGENIC COMPOUND | UNIVERSITY COLLEGE DUBLIN - NATIONAL UNIVERSITY OF IRELAND, DUBLIN (IE) | 2013-10-31 | — | — | US | disclosed |
| US-20130289066-A1 | ANTI-ANGIOGENIC COMPOUND | UNIVERSITY COLLEGE DUBLIN - NATIONAL UNIVERSITY OF IRELAND, DUBLIN (IE) | 2013-10-31 | — | — | US | disclosed |
| WO-2012095836-A1 | ANTI-ANGIOGENIC COMPOUND | UNIVERSITY COLLEGE DUBLIN - NATIONAL UNIVERSITY OF IRELAND, DUBLIN (IE) | 2012-07-19 | — | — | WO | disclosed |
| US-4130650-A | 1-METHYL- OR DIMETHYL-AMINOETHOXY, 2-PYRIDYLVINYL-BENZENE | BOEHRINGER INGELHEIM GMBH (DE) | 1978-12-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150218100-A1 | ANTI-ANGIOGENIC COMPOUNDS | VEGFA, FLT4, VHL | ECE2 13/4885NPC1 2305/4885RAB9A 1336/4885 |
| US-20130289066-A1 | ANTI-ANGIOGENIC COMPOUND | VEGFA, FLT4, FLT1 | ECE2 26/4885NPC1 3260/4885RAB9A 3958/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.