SCHEMBL1032545

SCHEMBL1032545

O=C(O)CCCC(C(=O)O)(C(=O)O)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.53
SLC22A6 Q4U2R8 2/20 0.53
TSHR P16473 5/20 0.50
NFKB1 P19838 2/20 0.50
PMP22 Q01453 1/20 0.50
CAMK2A Q9UQM7 1/20 0.46
HDAC11 Q96DB2 4/20 0.43
KMT2A Q03164 2/20 0.43
GABRR3 A8MPY1 1/20 0.43
GABRP O00591 1/20 0.43
GABRD O14764 1/20 0.43
HDAC3 O15379 1/20 0.43
GABBR2 O75899 1/20 0.43
CYP1A2 P05177 1/20 0.43
THRB P10828 1/20 0.43
GABRA1 P14867 1/20 0.43
GABRB1 P18505 1/20 0.43
GABRG2 P18507 1/20 0.43
GABRR1 P24046 1/20 0.43
GABRB3 P28472 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18190941 0.92 LMNA (0.58) LMNASLC22A6TSHRNFKB1PMP22
SCHEMBL18190942 0.90 TSHR (0.60) LMNASLC22A6TSHRNFKB1PMP22
SCHEMBL6129298 0.90 TSHR (0.60) LMNASLC22A6TSHRNFKB1PMP22
SCHEMBL4459811 0.90 TSHR (0.60) LMNASLC22A6TSHRNFKB1PMP22
SCHEMBL3261834 0.90 TSHR (0.60) LMNASLC22A6TSHRNFKB1PMP22
SCHEMBL176224 0.90 TSHR (0.60) LMNASLC22A6TSHRNFKB1PMP22
SCHEMBL165858 0.90 TSHR (0.60) LMNASLC22A6TSHRNFKB1PMP22
SCHEMBL11877708 0.87 LMNA (0.64) LMNASLC22A6TSHRNFKB1PMP22
SCHEMBL3925193 0.85 LMNA (0.43) LMNASLC22A6TSHRNFKB1PMP22
SCHEMBL4555671 0.82 LMNA (0.47) LMNASLC22A6TSHRNFKB1PMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024124258-A2 METHODS OF PREPARING STABLE NUCLEIC ACID LIQUID FORMULATIONS UNIVERSITY OF NORTH CAROLINA AT WILMINGTON (US) 2024-06-13 WO claimed
EP-2485880-A1 IMPREGNATION OF CHEMICALS INTO WOOD UPM-Kymmene Wood Oy (FI) 2012-08-15 EP claimed
WO-2011042609-A1 IMPREGNATION OF CHEMICALS INTO WOOD UPM-KYMMENE WOOD OY (FI) 2011-04-14 WO claimed
CN-1898317-B Composition and method for controlling crystallization rate of polyolefin-based resin, resin composition, and resin molded article NEW JAPAN CHEM CO LTD 2010-11-24 CN claimed
CN-1830679-B Recording paper and method for recording image using the same FUJI XEROX CORP 2010-06-23 CN claimed
CN-1898317-A Composition and method for controlling crystallization rate of polyolefin-based resin, resin composition, and resin molded article NEW JAPAN CHEM CO LTD (JP) 2007-01-17 CN claimed
CN-1091127-C Benzotriazole UV absorbers having enhanced durability CIBA SC HOLDING AG (CH) 2002-09-18 CN claimed
EP-1114096-A1 PLASTIC COMPOSITION WITH IMPROVED WEATHER RESISTANCE DSM N.V. (NL) 2001-07-11 EP claimed
EP-0994855-A1 LIGHT-STABILIZING SYNERGIC MIXTURES FOR ORGANIC POLYMERS Great Lakes Chemical (Europe) GmbH (CH) 2000-04-26 EP claimed
WO-2000009604-A1 PLASTIC COMPOSITION WITH IMPROVED WEATHER RESISTANCE DSM N.V. (NL) 2000-02-24 WO claimed
EP-0960160-A1 PLASTICS COMPOSITION HAVING IMPROVED WEATHER RESISTANCE DSM N.V. (NL) 1999-12-01 EP claimed
WO-1999048965-A1 PLASTICS COMPOSITION WITH IMPROVED WEATHER RESISTANCE DSM N.V. (NL) 1999-09-30 WO claimed
EP-0896642-A1 PROCESS FOR THE PREPARATION OF TETRAALKYL 1,2,3,4-BUTANETETRACARBOXYLATES MONSANTO COMPANY (US) 1999-02-17 EP claimed
WO-1999002495-A1 LIGHT-STABILIZING SYNERGIC MIXTURES FOR ORGANIC POLYMERS GREAT LAKES CHEMICAL (EUROPE) GMBH (CH) 1999-01-21 WO claimed
WO-1998036023-A1 PLASTICS COMPOSITION HAVING IMPROVED WEATHER RESISTANCE DSM N.V. (NL) 1998-08-20 WO claimed
CN-1183442-A Benzotriazole UV absorbers having enhanced durability CIBA SC HOLDING AG (CH) 1998-06-03 CN claimed
WO-1997026389-A1 PROCESS FOR THE PREPARATION OF TETRAALKYL 1,2,3,4-BUTANETETRACARBOXYLATES MONSANTO COMPANY (US) 1997-07-24 WO claimed
CN-1052514-A The preparation method of butanetetra-carboxylic acid MONSANTO CO (US) 1991-06-26 CN claimed
EP-4384575-A1 LASER TRANSPARENT COMPOSITION AND MOLDED ARTICLES MADE THEREFROM Celanese International Corporation (US) 2024-06-19 EP disclosed
US-4305824-A Cellulose derivative reverse osmosis membrane TORAY INDUSTRIES, INCORPORATED (JP) 1981-12-15 US disclosed