Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 3/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 7/20 | 0.34 |
| ▸ | TACR2 | P21452 | 2/20 | 0.33 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.33 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.33 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.33 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.33 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.32 |
| ▸ | NT5E | P21589 | 1/20 | 0.32 |
| ▸ | EDNRA | P25101 | 2/20 | 0.32 |
| ▸ | CDC25B | P30305 | 5/20 | 0.31 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.31 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.31 |
| ▸ | EDNRB | P24530 | 1/20 | 0.31 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14617865 | 1.00 | ERN1 (0.38) | ERN1PTPN1TACR2SSTR1SSTR2 | |
| SCHEMBL2087673 | 0.94 | ERN1 (0.39) | ERN1PTPN1TACR2SSTR1SSTR2 | |
| SCHEMBL16090884 | 0.91 | ERN1 (0.39) | ERN1EDNRATUBB1EDNRB | |
| SCHEMBL10177099 | 0.86 | ERN1 (0.39) | ERN1EDNRATUBB1EDNRB | |
| SCHEMBL16727618 | 0.84 | ERN1 (0.40) | ERN1EDNRATUBB1EDNRB | |
| SCHEMBL10328080 | 0.83 | GJB2 (0.33) | PTPN1TACR2SSTR1SSTR2SSTR4 | |
| SCHEMBL14617864 | 0.83 | GJB2 (0.33) | PTPN1TACR2SSTR1SSTR2SSTR4 | |
| SCHEMBL16727619 | 0.83 | GJB2 (0.33) | PTPN1TACR2SSTR1SSTR2SSTR4 | |
| SCHEMBL2089094 | 0.77 | PTPN1 (0.35) | PTPN1TACR2SSTR1SSTR2SSTR4 | |
| SCHEMBL18511211 | 0.77 | PTPN1 (0.35) | PTPN1TACR2SSTR1SSTR2SSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120178680-A1 | GLYCOSIDE DERIVATIVES AND USES THEREOF | NOVARTIS AG (CH) | 2012-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120178680-A1 | GLYCOSIDE DERIVATIVES AND USES THEREOF | SLC5A1, SLC5A2, SLC2A1 | ERN1 2914/4885PTPN1 723/4885TACR2 2146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.