SCHEMBL103294

SCHEMBL103294

C=Cc1ccc(OCOc2ccc(OC(=O)c3ccc(C=C)cc3)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.47
MAPT P10636 6/20 0.47
GFER P55789 1/20 0.47
RAB9A P51151 1/20 0.45
HSD17B10 Q99714 1/20 0.43
PARP10 Q53GL7 1/20 0.42
PRSS1 P07477 2/20 0.42
ACR P10323 1/20 0.42
F2 P00734 1/20 0.41
PRSS2 P07478 1/20 0.41
PRSS3 P35030 1/20 0.41
NPC1 O15118 2/20 0.41
LMNA P02545 2/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
KDM4E B2RXH2 2/20 0.40
NFKB1 P19838 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13310808 1.00 KMT2A (0.47) KMT2AMAPTGFERRAB9AHSD17B10
SCHEMBL16812851 0.90 KMT2A (0.54) KMT2AMAPTGFERRAB9AHSD17B10
SCHEMBL103296 0.90 KMT2A (0.54) KMT2AMAPTGFERRAB9AHSD17B10
SCHEMBL13032731 0.90 KMT2A (0.48) KMT2AMAPTGFERRAB9APRSS1
SCHEMBL104020 0.87 MAPT (0.48) KMT2AMAPTGFERRAB9APRSS1
SCHEMBL12931954 0.86 MAPT (0.41) KMT2AMAPTGFERRAB9APRSS1
SCHEMBL14087748 0.85 MAPT (0.43) KMT2AMAPTGFERRAB9AHSD17B10
SCHEMBL16812836 0.85 KMT2A (0.50) KMT2AMAPTGFERRAB9AHSD17B10
SCHEMBL12931949 0.85 KMT2A (0.50) KMT2AMAPTGFERRAB9AHSD17B10
SCHEMBL103307 0.84 HPGD (0.36) KMT2AMAPTGFERRAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10011773-B2 Liquid crystal display device DIC CORPORATION (JP) 2018-07-03 US disclosed
US-9828548-B2 Liquid-crystal composition DIC CORPORATION (JP) 2017-11-28 US disclosed
US-9809752-B2 Liquid crystal display device DIC CORPORATION (JP) 2017-11-07 US disclosed
US-9410086-B2 Liquid crystal-polymer composite material DIC CORPORATION (JP) 2016-08-09 US disclosed
US-20160215217-A1 LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2016-07-28 US disclosed
US-20160130502-A1 LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2016-05-12 US disclosed
US-20150259600-A1 LIQUID-CRYSTAL COMPOSITION DIC CORPORATION (JP) 2015-09-17 US disclosed
US-8992796-B2 Polymerizable liquid crystal composition DIC CORPORATION (JP) 2015-03-31 US disclosed
US-20140327862-A1 FERROELECTRIC LIQUID CRYSTAL COMPOSITION AND FERROELECTRIC LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2014-11-06 US disclosed
US-20140313468-A1 LIQUID CRYSTAL DISPLAY ELEMENT DIC CORPORATION (JP) 2014-10-23 US disclosed
US-8405799-B2 Polymer-stabilized liquid crystal composition, liquid crystal display device, method for producing liquid crystal display device DIC CORPORATION (JP) 2013-03-26 US disclosed
US-20120056129-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOSITION DIC CORPORATION (JP) 2012-03-08 US disclosed
US-7871540-B2 Polymerizable liquid crystal composition DIC CORPORATION (JP) 2011-01-18 US disclosed
US-20100149446-A1 POLYMER-STABILIZED LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL DISPLAY DEVICE, METHOD FOR PRODUCING LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2010-06-17 US disclosed
US-7622166-B2 birefringence layer includes a polymerizable liquid crystal having rodlike molecules and a fluoroalkylsilyl coupling agent and a surfactant that homeotropically align the polymerizable liquid crystal to form a crosslinked polymer in a state of homeotropic alignment; low cost, heat resistance DAI NIPPON PRINTING CO., LTD. (JP) 2009-11-24 US disclosed
US-20090059136-A1 COMPOSITE POLARIZING PLATE WITH WIDE FIELD OF VIEW AND LIQUID CRYSTAL DISPLAY SUMITOMOCHEMICAL COMPANY, LIMITED (JP) 2009-03-05 US disclosed
US-20090050844-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOSITION DIC CORPORATION (JP) 2009-02-26 US disclosed
US-7342623-B2 Optical element and liquid crystal display device using the same DAI NIPPON PRINTING CO., LTD. (JP) 2008-03-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090050844-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOSITION H1-0, H1-4, H1-10 KMT2A 1510/4885MAPT 1343/4885GFER 2929/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.