SCHEMBL10329435

SCHEMBL10329435

O=C1CC(OC2CC(=O)OC2=O)C(=O)O1

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.31
TSHR P16473 2/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2582980 0.80
SCHEMBL18785024 0.80
SCHEMBL2590394 0.80
SCHEMBL14634365 0.75 SMN1; SMN2 (0.30) SMN1; SMN2
SCHEMBL28675672 0.75 ALDH1A1 (0.36) SMN1; SMN2TSHRALDH1A1
SCHEMBL410612 0.73 POLB (0.34) TSHR
SCHEMBL28969037 0.73
SCHEMBL395069 0.73 POLB (0.34) TSHR
SCHEMBL395068 0.73 POLB (0.34) TSHR
SCHEMBL29539236 0.73 POLB (0.34) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2493991-B1 ANTIREFLECTIVE COMPOSITION FOR PHOTORESISTS MERCK PATENT GMBH (DE) 2016-03-02 EP disclosed
EP-2300518-B1 ANTIREFLECTIVE COATING COMPOSITIONS AZ ELECTRONIC MATERIALS USA (US) 2012-08-15 EP disclosed
US-8221965-B2 Antireflective coating compositions AZ ELECTRONIC MATERIALS USA CORP. (US) 2012-07-17 US disclosed
US-8221965-B2 Antireflective coating compositions AZ ELECTRONIC MATERIALS USA CORP. (US) 2012-07-17 US disclosed
US-20100009293-A1 Antireflective Coating Compositions MERCK PATENT GMBH (DE) 2010-01-14 US disclosed
US-20100009293-A1 Antireflective Coating Compositions MERCK PATENT GMBH (DE) 2010-01-14 US disclosed
WO-2010004377-A1 ANTIREFLECTIVE COATING COMPOSITIONS AZ ELECTRONIC MATERIALS USA CORP. (US) 2010-01-14 WO disclosed
US-7638262-B2 Antireflective composition for photoresists AZ ELECTRONIC MATERIALS USA CORP. (US) 2009-12-29 US disclosed
US-20080038659-A1 Antireflective composition for photoresists MERCK PATENT GMBH (DE) 2008-02-14 US disclosed