SCHEMBL10329674

SCHEMBL10329674

CCCCCCCCCCCCc1cc(C)sc1-c1nc2sc(-c3sc(-c4cc(CCCCCCCCCCCC)c(-c5sc(C)cc5CCCCCCCCCCCC)s4)cc3CCCCCCCCCCCC)nc2s1

nearest known ligand 0.32

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 4/20 0.31
PTGS2 P35354 3/20 0.31
TYR P14679 2/20 0.31
MEN1 O00255 1/20 0.31
TP53 P04637 1/20 0.31
CYP3A4 P08684 1/20 0.31
MAPT P10636 1/20 0.31
ALOX15 P16050 1/20 0.31
TSHR P16473 1/20 0.31
HTT P42858 1/20 0.31
KMT2A Q03164 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
KCNH2 Q12809 1/20 0.30
ADORA2A P29274 1/20 0.30
TLR8 Q9NR97 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10329659 1.00 ALOX5 (0.31) ALOX5PTGS2TYRMEN1TP53
SCHEMBL10329658 1.00 ALOX5 (0.31) ALOX5PTGS2TYRMEN1TP53
SCHEMBL10329672 1.00 ALOX5 (0.31) ALOX5PTGS2TYRMEN1TP53
SCHEMBL20279204 0.95 ALOX5 (0.31) ALOX5PTGS2TYRMEN1TP53
SCHEMBL10001313 0.95 ALOX5 (0.31) ALOX5PTGS2TYRMEN1TP53
SCHEMBL17676339 0.94
SCHEMBL10329670 0.93 ALOX5 (0.34) ALOX5PTGS2TYRMEN1TP53
SCHEMBL10329662 0.93 ALOX5 (0.34) ALOX5PTGS2TYRMEN1TP53
SCHEMBL16204082 0.93 ALOX5 (0.34) ALOX5PTGS2TYRMEN1TP53
SCHEMBL10329668 0.93 ALOX5 (0.34) ALOX5PTGS2TYRMEN1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8222633-B2 Organic transistor using thiazolothiazole derivatives and method for fabricating the same LG CHEM, LTD. (KR) 2012-07-17 US disclosed
US-20100012930-A1 ORGANIC TRANSISTOR USING THIAZOLOTHIAZOLE DERIVATIVES AND METHOD FOR FABRICATING THE SAME LG CHEM, LTD. (KR) 2010-01-21 US disclosed