Acetic Acid

Acetic Acid

SCHEMBL103302

CC(=O)O.CCC(N)(CC)C(=O)O

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NOS3 known ✓ P29474 1/20 0.43
NOS1 known ✓ P29475 1/20 0.43
NOS2 known ✓ P35228 1/20 0.43
MEN1 O00255 2/20 0.60
CYP1A2 P05177 2/20 0.60
KMT2A Q03164 2/20 0.60
ALDH1A1 P00352 2/20 0.60
THRB P10828 1/20 0.60
ARG1 P05089 7/20 0.50
ARG2 P78540 7/20 0.50
ODC1 P11926 1/20 0.41
FFAR3 O14843 2/20 0.39
LCK P06239 1/20 0.39
FYN P06241 1/20 0.39
GRM2 Q14416 1/20 0.38
GRM3 Q14832 1/20 0.38
TDP1 Q9NUW8 1/20 0.33
GGT1 P19440 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL58260 0.94
Hydrochloric Acid SCHEMBL1133986 0.92 MEN1 (0.62) MEN1CYP1A2KMT2AALDH1A1THRB
SCHEMBL22615903 0.82 ALDH1A1 (0.54) MEN1CYP1A2KMT2AALDH1A1THRB
SCHEMBL5323365 0.81
SCHEMBL2458445 0.81
SCHEMBL1651824 0.81
SCHEMBL1650712 0.81
Acrylic Acid SCHEMBL29238214 0.80 ALDH1A1 (0.52) MEN1CYP1A2KMT2AALDH1A1THRB
Hydrochloric Acid SCHEMBL31367633 0.80 ALDH1A1 (0.52) MEN1CYP1A2KMT2AALDH1A1THRB
SCHEMBL28719235 0.80 MEN1 (0.52) MEN1CYP1A2KMT2AALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 773 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3566693-B1 EYE DEVICE EYED PHARMA (BE) 2021-02-17 EP claimed
EP-3566693-A1 EYE DEVICE EyeD Pharma (BE) 2019-11-13 EP claimed
EP-3068372-B1 EYE DEVICE EYED PHARMA (BE) 2019-05-08 EP claimed
US-9999595-B2 Eye device EYED PHARMA (BE) 2018-06-19 US claimed
EP-2305624-B1 Self-degradable explosive device MAXAMCORP HOLDING SL (ES) 2017-09-27 EP claimed
US-20160287513-A1 EYE DEVICE EYED PHARMA (BE) 2016-10-06 US claimed
EP-3068372-A1 EYE DEVICE EyeD Pharma (BE) 2016-09-21 EP claimed
EP-2931278-A1 ORAL FORM, COMPRISING IMMEDIATE-RELEASE COATED PARTICLES OF AT LEAST ONE ACTIVE COMPOUND THAT ARE GRINDING-RESISTANT Flamel Ireland Limited (IE) 2015-10-21 EP claimed
US-9149439-B2 Multi-particulate, modified-release composition SANDOZ AG (CH) 2015-10-06 US claimed
WO-2015071427-A1 EYE DEVICE EYED PHARMA (BE) 2015-05-21 WO claimed
US-20040208925-A1 Dispersible alendronate microparticle formulation SANOVEL ILAC SANAYI VE TICARET ANONIM SIRKETI 2004-10-21 US claimed
US-20040115268-A1 Systemic delivery of antiviral agents CONTROL DELIVERY SYSTEMS, INC. 2004-06-17 US claimed
WO-2004050066-A1 MICROSPHERES AND RELATED PROCESSES AND PHARMACEUTICAL COMPOSITIONS THE UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2004-06-17 WO claimed
WO-2004043435-A2 SYSTEMIC DELIVERY OF ANTIVIRAL AGENTS CONTROL DELIVERY SYSTEMS, INC. (US) 2004-05-27 WO claimed
WO-2003092660-A1 MONOCOMPARTMENT OSMOTIC CONTROLLED DRUG DELIVERY SYSTEM RANBAXY LABORATORIES LIMITED (US) 2003-11-13 WO claimed
US-5540945-A Pharmaceutical preparations for oral administration that are adapted to release the drug at appropriate sites in the intestines CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 1996-07-30 US claimed
US-5025004-A Water-dispersible polymeric compositions EASTMAN KODAK COMPANY (US) 1991-06-18 US claimed
EP-0063014-B1 A METHOD OF PREPARING COATED SOLID PREPARATIONS SANKYO COMPANY LIMITED (JP) 1985-08-14 EP claimed
US-4533562-A Method of preparing coated solid preparations SANKYO COMPANY, LIMITED (JP) 1985-08-06 US claimed
EP-0063014-A2 A method of preparing coated solid preparations SANKYO COMPANY LIMITED (JP) 1982-10-20 EP claimed