⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5821553 | 0.77 | ALOX5 (0.77) | — | |
| SCHEMBL16611743 | 0.76 | — | — | |
| SCHEMBL5490909 | 0.76 | — | — | |
| SCHEMBL12763758 | 0.76 | GAA (0.46) | — | |
| SCHEMBL11401598 | 0.76 | ALOX5 (0.81) | — | |
| SCHEMBL9482792 | 0.76 | ALOX5 (0.81) | — | |
| Hydrochloric Acid SCHEMBL11405250 | 0.74 | ALOX5 (0.78) | — | |
| Hydrochloric Acid SCHEMBL11397911 | 0.74 | ALOX5 (0.78) | — | |
| Hydrochloric Acid SCHEMBL11410027 | 0.74 | ALOX5 (0.78) | — | |
| Hydrochloric Acid SCHEMBL11411704 | 0.74 | ALOX5 (0.78) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022221704-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING CANCER | HOTSPOT THERAPEUTICS, INC. (US) | 2022-10-20 | — | — | WO | disclosed |
| CN-113227851-A | Liquid crystal composition, method for producing polymeric liquid crystalline compound, light-absorbing anisotropic film, laminate, and image display device | 富士胶片株式会社 | 2021-08-06 | — | — | CN | disclosed |
| CN-111094292-A | Pyrazolo [1,5a ] pyrimidine derivatives as IRAK4 modulators | 豪夫迈·罗氏有限公司 | 2020-05-01 | — | — | CN | disclosed |
| EP-2439204-B1 | HETEROCYCLIC COMPOUND AND HEMATOPOIETIC STEM CELL AMPLIFIER | NISSAN CHEMICAL IND LTD (JP) | 2017-01-04 | — | — | EP | disclosed |
| US-20120184526-A1 | COMPOUNDS AND COMPOSITIONS AS SYK KINASE INHIBITORS | IRM LLC (BM) | 2012-07-19 | — | — | US | disclosed |
| CN-100392108-C | Composition and use thereof | TFL LEDERTECHNIK GMBH (DE) | 2008-06-04 | — | — | CN | disclosed |
| CN-1625605-A | Composition and use thereof | TFL LEDERTECHNIK GMBH (DE) | 2005-06-08 | — | — | CN | disclosed |
| EP-0267264-A1 | HIGH CONTRAST DEVELOPMENT OF PHOTOGRAPHIC ELEMENTS. | EASTMAN KODAK CO (US) | 1988-05-18 | — | — | EP | disclosed |
| WO-1987007039-A2 | HIGH CONTRAST DEVELOPMENT OF PHOTOGRAPHIC ELEMENTS | EASTMAN KODAK COMPANY (US) | 1987-11-19 | — | — | WO | disclosed |