SCHEMBL10332181

SCHEMBL10332181

Nc1ccc2cc(S(=O)(=O)O)cc(O)c2c1.[Na]

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NT5E P21589 4/20 1.00
CASP6 P55212 4/20 0.76
NSD2 O96028 3/20 0.76
DUSP3 P51452 2/20 0.76
PTPN5 P54829 2/20 0.76
PTPN11 Q06124 2/20 0.76
ALDH1A1 P00352 4/20 0.60
HSD17B10 Q99714 4/20 0.60
CYP2C9 P11712 3/20 0.60
CYP2C19 P33261 2/20 0.60
CASP7 P55210 1/20 0.56
CTDSP1 Q9GZU7 2/20 0.53
TSHR P16473 3/20 0.50
TDP1 Q9NUW8 1/20 0.50
PRMT1 Q99873 1/20 0.49
CYP1A2 P05177 3/20 0.42
PLAU P00749 1/20 0.41
PTPRA P18433 1/20 0.40
PTPRB P23467 1/20 0.40
HIF1A Q16665 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10623050 1.00 NT5E (1.00) NT5ECASP6NSD2DUSP3PTPN5
SCHEMBL156692 1.00 NT5E (1.00) NT5ECASP6NSD2DUSP3PTPN5
Water SCHEMBL7701819 0.98 NT5E (0.97) NT5ECASP6NSD2DUSP3PTPN5
SCHEMBL4113779 0.98 NT5E (0.97) NT5ECASP6NSD2DUSP3PTPN5
SCHEMBL11309339 0.98 NT5E (0.97) NT5ECASP6NSD2DUSP3PTPN5
SCHEMBL9776668 0.98 NT5E (0.97) NT5ECASP6NSD2DUSP3PTPN5
SCHEMBL16552797 0.94 CASP6 (0.88) NT5ECASP6NSD2DUSP3PTPN5
Phenol SCHEMBL11722025 0.91 NT5E (0.83) NT5ECASP6NSD2DUSP3PTPN5
SCHEMBL7900032 0.90 NT5E (0.81) NT5ECASP6NSD2DUSP3PTPN5
SCHEMBL11022672 0.88 NT5E (0.78) NT5ECASP6NSD2DUSP3PTPN5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102408754-B Brightening disperse red 3B dye composition and preparation method thereof UNIV SOOCHOW 2014-01-08 CN claimed
CN-102408754-A Brightening disperse red 3B dye composition and preparation method thereof UNIV SOOCHOW 2012-04-11 CN claimed
CN-102408754-B Brightening disperse red 3B dye composition and preparation method thereof UNIV SOOCHOW 2014-01-08 CN disclosed
CN-102408754-A Brightening disperse red 3B dye composition and preparation method thereof UNIV SOOCHOW 2012-04-11 CN disclosed
US-4973672-A Water-soluble aminonaphthol disazo dyestuffs, their preparation and their use CASSELLA AKTIENGESELLSCHAFT (DE) 1990-11-27 US disclosed